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PMID: 6328429 Published · ppublish English Comparative Study Journal Article

Nucleotide sequence of two rasH related-genes isolated from the yeast Saccharomyces cerevisiae.

Nucleic acids research ·Vol. 12 ·No. 8 ·1984-04-25 ·Pages 3611-8

Dhar R, Nieto A, Koller R, DeFeo-Jones D, Scolnick EM

Abstract

A complete nucleotide sequence of two ras-related yeast genes (c- rassc -1 and c- rassc -2) isolated from the yeast strain Saccharomyces cerevisiae is reported. They encode predicted polypeptides of 40,000 and 41,000 daltons, respectively. The N-terminal 170 amino acids from both genes show extensive amino acid homology to other ras genes from vertebrates, whereas their C-termini have diverged. These genes should be useful in the elucidation of a normal biological function of ras-related genes in a simple system like yeast.

MeSH Terms
Amino Acid Sequence Animals Base Sequence DNA, Fungal/genetics Fungal Proteins/genetics Genes, Fungal Mice Molecular Weight Oncogenes Saccharomyces cerevisiae/genetics Sarcoma Viruses, Murine/genetics Species Specificity
Chemicals
DNA, Fungal Fungal Proteins
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Dhar R
Nieto A
Koller R
DeFeo-Jones D
Scolnick E M
References (16)
16 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
Published
1984-04-25
Pages
3611-8
Language
English
Region
England
NLM ID
0411011
PMCID
PMC318772
Subset
IM
Databases
GENBANK
X00527, X00528
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