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PMID: 6403461 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Reacquisition of specific proteins confers virulence in Mycoplasma pneumoniae.

Infection and immunity ·Vol. 39 ·No. 2 ·1983-02-00 ·Pages 830-6

Krause DC, Leith DK, Baseman JB

Abstract

Hemadsorbing revertants were isolated from spontaneous hemadsorption-negative, avirulent mutants of Mycoplasma pneumoniae. The revertants simultaneously reacquired specific proteins absent in their homologous mutants, along with neuraminidase-sensitive adherence to the respiratory epithelium and virulence. Peptide mapping and immunological analysis indicated no precursor-product relationships among certain of these proteins.

MeSH Terms
Adhesiveness Animals Bacterial Proteins/physiology Cricetinae Hemadsorption Lung/microbiology Mesocricetus Mutation Mycoplasma pneumoniae/analysis,genetics,pathogenicity Peptides/analysis
Chemicals
Bacterial Proteins Peptides
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Krause D C
Leith D K
Baseman J B
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25 references, click to expand
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.39.2.830-836.1983
Published
1983-02-00
Pages
830-6
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC348024
Subset
IM
Grants
NHLBI NIH HHS · HL-19171 · United States
External Links
PubMed source DOI: 10.1128/iai.39.2.830-836.1983 PMC Full Text View journal details
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