A study of the specific IgM antibody response in Mycoplasma pneumoniae infection in man.
Sera from 96 patients with Mycoplasma pneumoniae infection were examined for specific IgM antibody. The complement fixation test was used to measure the IgM after separation by ultracentrifugation through sucrose density gradients. Of patients under the age of 20 years 78% displayed positive specific IgM titres. In older patients only 34% were IgM positive. The specific IgM remained detectable, but at decreasing levels, during the follow-up period of 5 months. This diagnostic technique appears to be of value in children and young adults experiencing primary infection with M. pneumoniae.
12 references, click to expand
-
On the nature of complement-fixing antibodies to Mycoplasma pneumoniae.J Immunol. 1966 Jul;97(1):95-9 PMID: 5920459
-
Serum IgM and IgG responses in postnatally acquired rubella.Lancet. 1969 Jul 12;2(7611):65-8 PMID: 4182759
-
An aid to the rapid diagnosis of Mycoplasma pneumoniae infections.J Infect Dis. 1969 Jun;119(6):650-3 PMID: 5795105
-
Persistence of serum antibody following Mycoplasma pneumoniae infection.Am Rev Respir Dis. 1970 Apr;101(4):620-2 PMID: 5439883
-
A survey of antibodies to Mycoplasma pneumoniae in Queensland.Med J Aust. 1970 Apr 18;1(16):800-2 PMID: 5427638
-
Antibody responses in Mycoplasms pneumoniae infection in relation to serum immunoglobulins, especially IgM.Acta Pathol Microbiol Scand B Microbiol Immunol. 1971;79(5):620-34 PMID: 4938674
-
The diagnostic value of determination of IgM antibodies against Mycoplasma pneumoniae by the indirect immunofluorescent antibody test.Acta Pathol Microbiol Scand B. 1976 Aug;84(4):170-6 PMID: 785942
-
Passive hemagglutination and complement fixation reactions in the early diagnosis of Mycoplasma pneumoniae infections.Virologie. 1976 Oct-Dec;27(4):229-35 PMID: 1006981
-
The treatment of Mycoplasma pneumoniae infections.Scott Med J. 1977 Dec;22(5):361-5 PMID: 601554
-
Determination of IgG, IgM, and IgA antibodies to Mycoplasma pneumoniae by an indirect staphylococcal radioimmunoassy.Med Microbiol Immunol. 1978 May 26;165(1):29-41 PMID: 661748
-
Serological diagnosis of Mycoplasma pneumoniae infection by enzyme immunoassay.J Clin Pathol. 1980 Sep;33(9):836-40 PMID: 6776157
-
Technique of complementfixation test applicable to the diagnosis of virus diseases.Mon Bull Minist Health Public Health Lab Serv. 1962 May;21:96-104 PMID: 13872351
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