Production of enterotoxin by Yersinia enterocolitica.

Infection and immunity ·Vol. 19 ·No. 3 ·1978-03-00 ·Pages 908-11

Pai CH, Mors V

Abstract

Forty-three strains of Yersinia enterocolitica isolated from children with gastroenteritis and 18 laboratory strains were examined for enterotoxin production by using the infant mouse, Y1 adrenal cell, and rabbit ileal loop assay systems. All clinical isolates and seven laboratory strains were found enterotoxigenic in the infant mouse model, but none of the strains produced toxin in the Y1 adrenal cell system. One enterotoxin-producing strain was also tested by the rabbit ileal loop assay, confirming the results of the infant mouse assay. The enterotoxin was heat-stable and as active in the 6-h rabbit ileal loop as in the 18-h assay, suggesting a similarity to the heat-stable enterotoxin of Escherichia coli.

MeSH Terms

Animals Bacterial Toxins/biosynthesis Biological Assay Cells, Cultured Child Enterotoxins/biosynthesis Gastroenteritis/microbiology Humans Mice Rabbits Serotyping Temperature Yersinia/classification,metabolism

Chemicals

Bacterial Toxins Enterotoxins

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Pai C H

Mors V

References (16)

16 references, click to expand

Diarrhoea associated with heat-stable enterotoxin-producing strains of Escherichia coli.
Lancet. 1975 Aug 9;2(7928):239-41 PMID: 49793
Laboratory investigation of diarrhea in travelers to Mexico: evaluation of methods for detecting enterotoxigenic Echerichia coli.
J Clin Microbiol. 1976 May;3(5):486-95 PMID: 180047
Yersinia enterocolitica infection in patients with acute surgical abdominal disease. A prospective study.
Scand J Infect Dis. 1976;8(3):189-94 PMID: 788144
Yersinia enterocolitica: recovery and characterization of two unusual isolates from a case of acute enteritis.
J Clin Microbiol. 1977 Mar;5(3):341-5 PMID: 856866
Yersinia enterocolitica septicemia with septic arthritis.
Arch Intern Med. 1976 Nov;136(11):1305-8 PMID: 984993
Test for enterotoxigenic Escherichia coli using Y-1 adrenal cells in miniculture.
Infect Immun. 1975 Feb;11(2):334-6 PMID: 1089601
Heat-stable Escherichia coli enterotoxin production in vivo.
Infect Immun. 1975 Aug;12(2):240-4 PMID: 1097335
Pathogenecity of Yersinia enterocolitica for mice.
Infect Immun. 1975 Jan;11(1):164-70 PMID: 1116874
Generalized Yersinia enterocolitica infection.
J Infect Dis. 1975 Apr;131(4):447-51 PMID: 1117199
Arthritis associated with Yersinia enterocolitica infections.
Scand J Infect Dis. 1975;7(3):191-5 PMID: 1179174
Lung abscess and osteomyelitis of rib due to Yersinia enterocolitica.
Chest. 1976 Apr;69(4):546-8 PMID: 1261324
Survey on the incidence of Yersinia enterocolitica infection in Canada.
Appl Microbiol. 1974 Sep;28(3):469-73 PMID: 4472776
Test for Escherichia coli enterotoxin using infant mice: application in a study of diarrhea in children in Honolulu.
J Infect Dis. 1972 Apr;125(4):407-11 PMID: 4553083
Differences in the response of rabbit small intestine to heat-labile and heat-stable enterotoxins of Escherichia coli.
Infect Immun. 1973 Jun;7(6):873-80 PMID: 4577415
Experimental Yersinia enterocolitica infection in mice: kinetics of growth.
Infect Immun. 1974 May;9(5):851-7 PMID: 4596277
Experimental shigella keratoconjunctivitis; a preliminary report.
Acta Microbiol Acad Sci Hung. 1955;2(3):293-6 PMID: 14387586

Article Info

Journal

Infection and immunity

Abbr.

Infect Immun

ISSN

0019-9567

DOI

10.1128/iai.19.3.908-911.1978

Published

1978-03-00

Pages

908-11

Language

English

Region

United States

NLM ID

0246127

PMCID

PMC422276

Subset

External Links

PubMed source DOI: 10.1128/iai.19.3.908-911.1978 PMC Full Text View journal details

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Production of enterotoxin by Yersinia enterocolitica.

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