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PMID: 6788697 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Genetics of serum resistance in Neisseria gonorrhoeae: the sac-1 genetic locus.

Infection and immunity ·Vol. 32 ·No. 2 ·1981-05-00 ·Pages 547-52

Cannon JG, Lee TJ, Guymon LF, Sparling PF

Abstract

A genetic locus affecting susceptibility to the bactericidal activity of normal human serum has been designated sac-1. This locus was shown to be closely linked to, but not identical with, a second locus (designated nmp-2) that affects protein 1 of the outer membrane. The sac-1 locus could be linked to known antibiotic resistance markers on the gonococcal chromosome by genetic transformation.

MeSH Terms
Anti-Bacterial Agents/pharmacology Bacterial Proteins/genetics Blood Bactericidal Activity Chromosome Mapping Chromosomes, Bacterial Drug Resistance, Microbial Genes Genetic Linkage Neisseria gonorrhoeae/genetics,physiology Transformation, Bacterial
Chemicals
Anti-Bacterial Agents Bacterial Proteins
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Cannon J G
Lee T J
Guymon L F
Sparling P F
References (20)
20 references, click to expand
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.32.2.547-552.1981
Published
1981-05-00
Pages
547-52
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC351481
Subset
IM
Grants
NIAID NIH HHS · AI15036 · United States
External Links
PubMed source DOI: 10.1128/iai.32.2.547-552.1981 PMC Full Text View journal details
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