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PMID: 6886412 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Gentamicin-resistant staphylococci: genetics of an outbreak in a dermatology department.

The Journal of hygiene ·Vol. 91 ·No. 1 ·1983-08-00 ·Pages 7-16

Naidoo J, Noble WC, Weissmann A, Dyke KG

Abstract

The genetics of gentamicin resistance in Staphylococcus aureus strains isolated during an outbreak of infection in dermatology department have been studied. The predominant strain of S. aureus did not appear to possess a plasmid mediating gentamicin resistance though one isolate yielded a plasmid coding for penicillin and gentamicin. Three distinct plasmids were isolated from other phage types of S. aureus which appeared towards the end of the epidemic. There appeared to be a stepwise loss of gentamicin resistance in the predominant strain.

MeSH Terms
Aminoglycosides/pharmacology Anti-Bacterial Agents/pharmacology Chromosomes, Bacterial Dermatology Disease Outbreaks/epidemiology Female Genes, Bacterial Gentamicins/pharmacology Germany, West Humans R Factors Skin Diseases, Infectious/epidemiology,microbiology Staphylococcal Infections/epidemiology,microbiology Staphylococcus aureus/drug effects,genetics
Chemicals
Aminoglycosides Anti-Bacterial Agents Gentamicins
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Naidoo J
Noble W C
Weissmann A
Dyke K G
References (15)
15 references, click to expand
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Article Info
Journal
The Journal of hygiene
Abbr.
J Hyg (Lond)
ISSN
0022-1724
DOI
10.1017/s0022172400059970
Published
1983-08-00
Pages
7-16
Language
English
Region
England
NLM ID
0375374
PMCID
PMC2129284
Subset
IM
External Links
PubMed source DOI: 10.1017/s0022172400059970 PMC Full Text View journal details
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