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PMID: 6924825 Published · ppublish English Journal Article

Synergism between vancomycin and gentamicin or tobramycin for methicillin-susceptible and methicillin-resistant Staphylococcus aureus strains.

Antimicrobial agents and chemotherapy ·Vol. 22 ·No. 5 ·1982-11-00 ·Pages 903-5

Watanakunakorn C, Tisone JC

Abstract

By the time-kill curve method, the combinations of vancomycin-gentamicin and vancomycin-tobramycin were shown to be synergistic against a majority of methicillin-susceptible and -resistant strains of Staphylococcus aureus.

MeSH Terms
Anti-Bacterial Agents/pharmacology Drug Synergism Gentamicins/pharmacology Methicillin/pharmacology Microbial Sensitivity Tests Penicillin Resistance Staphylococcus aureus/drug effects Tobramycin/pharmacology Vancomycin/pharmacology
Chemicals
Anti-Bacterial Agents Gentamicins Vancomycin Methicillin Tobramycin
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Watanakunakorn C
Tisone J C
References (9)
9 references, click to expand
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  4. Staphylococcus aureus endocarditis. Combined therapy with vancomycin and rifampin.
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  5. Antibiotic-tolerant Staphylococcus aureus.
    J Antimicrob Chemother. 1978 Nov;4(6):561-8 PMID: 251180
  6. Interaction between vancomycin and rifampin against Staphylococcus aureus.
    Antimicrob Agents Chemother. 1981 Jun;19(6):1089-91 PMID: 7271276
  7. Antistaphylococcal activity of rifampin with other antibiotics.
    J Infect Dis. 1981 Oct;144(4):365-71 PMID: 6270215
  8. The antibacterial action of vancomycin.
    Rev Infect Dis. 1981 Nov-Dec;3 suppl:S210-5 PMID: 6805065
  9. Treatment of infections due to methicillin-resistant Staphylococcus aureus.
    Ann Intern Med. 1982 Sep;97(3):376-8 PMID: 7114635
Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.22.5.903
Published
1982-11-00
Pages
903-5
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC185681
Subset
IM
External Links
PubMed source DOI: 10.1128/AAC.22.5.903 PMC Full Text View journal details
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