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PMID: 69726 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Identification of the Gross cell surface antigen associated with murine leukemia virus-infected cells.

Journal of virology ·Vol. 23 ·No. 2 ·1977-08-00 ·Pages 315-22

Ledbetter J, Nowinski RC

Abstract

The Gross cell surface antigen (GCSA) is produced by cells that are either exogenously infected with murine leukemia virus (MuLV) or are expressing endogenous MuLV genomes. In immune precipitation assays, GCSA was resolved into two serologically distinct 85,000- and 95,000-dalton viral proteins. These antigenic components are glycosylated forms of the polyprotein precursors of the MuLV internal structural proteins.

MeSH Terms
AKR murine leukemia virus/immunology Animals Antigens, Viral/analysis Cell Line Cell Membrane/immunology Cytotoxicity Tests, Immunologic Epitopes Glycoproteins/immunology Leukemia, Experimental Mice Molecular Weight Protein Precursors/immunology Viral Proteins/immunology
Chemicals
Antigens, Viral Epitopes Glycoproteins Protein Precursors Viral Proteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Ledbetter J
Nowinski R C
References (19)
19 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.23.2.315-322.1977
Published
1977-08-00
Pages
315-22
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC515833
Subset
IM
External Links
PubMed source DOI: 10.1128/JVI.23.2.315-322.1977 PMC Full Text View journal details
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