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PMID: 7024735 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Expression of the L11-L1 operon in mutants of Escherichia coli lacking the ribosomal proteins L1 or L11.

Molecular & general genetics : MGG ·Vol. 181 ·No. 2 ·1981-00-00 ·Pages 164-8

Stöffler G, Hasenbank R, Dabbs ER

Abstract

Using a variety of immunological techniques, the supernatant levels of ribosomal proteins were measured in mutants lacking the ribosomal proteins L1 or L11, and in wild-type strains. There was a 2.5--5-fold elevation of protein L11 level in the supernatant of strains lacking protein L1, compared to wild-type. In contrast, there was no elevation, but rather a diminution, in the corresponding L1 level in strains lacking protein L11, compared to wild-type. These results are consistent with a model for the control of expression of the L11-L1 operon in which protein L1 is an inhibitor of expression of that operon, but protein L11 is not. The supernatant concentrations of other proteins were indistinguishable in all strains.

MeSH Terms
Bacterial Proteins/deficiency,genetics,metabolism Escherichia coli/genetics Feedback Gene Expression Regulation Immunoelectrophoresis Mutation Operon Ribosomal Proteins/deficiency,genetics,metabolism
Chemicals
Bacterial Proteins Ribosomal Proteins ribosomal protein L1 ribosomal protein L11
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Stöffler G
Hasenbank R
Dabbs E R
References (20)
20 references, click to expand
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Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
DOI
10.1007/BF00268422
Published
1981-00-00
Pages
164-8
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00268422
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