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PMID: 7033962 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Evidence for major histocompatibility complex restriction in transplantation immunity.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 79 ·No. 1 ·1982-01-00 ·Pages 171-4

Silvers WK, Fleming HL, Naji A, Barker CF

Abstract

Studies on the survival of histocompatibility-Y antigen (H-Y)-incompatible and skin-specific antigen (Skn)-incompatible skin grafts in mice, as well as those concerned with the survival of cultured parathyroid allografts in rats, indicate that grafts provoke a strong immune response only if they include donor macrophages (or Langerhans cells) or if major histocompatibility complex-compatible macrophages are available to react with cells bearing the foreign antigens.

MeSH Terms
Animals Animals, Newborn Female Immune Tolerance Lymphocyte Transfusion Major Histocompatibility Complex Male Mice Mice, Inbred Strains Skin Transplantation Transplantation Immunology Transplantation, Homologous
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Silvers W K
Fleming H L
Naji A
Barker C F
References (37)
37 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.79.1.171
Published
1982-01-00
Pages
171-4
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC345684
Subset
IM
Grants
NIADDK NIH HHS · AM-26007 · United States
NCI NIH HHS · CA-09140 · United States
NCI NIH HHS · CA-18640 · United States
External Links
PubMed source DOI: 10.1073/pnas.79.1.171 PMC Full Text View journal details
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