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PMID: 7325645 Published · ppublish English Comparative Study Journal Article Research Support, U.S. Gov't, P.H.S.

Susceptibility of Pittsburgh pneumonia agent (Legionella micdadei) and other newly recognized members of the genus Legionella to nineteen antimicrobial agents.

Antimicrobial agents and chemotherapy ·Vol. 20 ·No. 6 ·1981-12-00 ·Pages 793-9

Pasculle AW, Dowling JN, Weyant RS, Sniffen JM, Cordes LG, Gorman GM, Feeley JC

Abstract

The susceptibilities of 11 strains representing the five recognized species of Legionella were determined by agar dilution testing on buffered charcoal-yeast extract agar. All of the legionellae tested were susceptible to rifampin, erythromycin, rosaramycin, chloramphenicol, and the aminoglycosides and were resistant to clindamycin and vancomycin. Susceptibilities to penicillins and cephalosporins were variable. Legionella micdadei, Legionella bozemanii, and Legionella gormanii were susceptible to these agents, but minimal inhibitory concentrations for each species were different. Legionella dumoffii resembled Legionella pneumophila in being resistant to penicillin, cephalothin, and cephamandole and susceptible to moxalactam and cefoxitin. All species except L. micdadei produced beta-lactamase.

MeSH Terms
Anti-Bacterial Agents/pharmacology Bacterial Infections/microbiology Culture Media Humans Legionella/drug effects Microbial Sensitivity Tests
Chemicals
Anti-Bacterial Agents Culture Media
Authors & Affiliations
7 authors, click to expand affiliations / ORCID
Pasculle A W
Dowling J N
Weyant R S
Sniffen J M
Cordes L G
Gorman G M
Feeley J C
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Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.20.6.793
Published
1981-12-00
Pages
793-9
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC181800
Subset
IM
Grants
NIAID NIH HHS · AI-17047 · United States
External Links
PubMed source DOI: 10.1128/AAC.20.6.793 PMC Full Text View journal details
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