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PMID: 737910 Published · ppublish English Journal Article

Defective yeast opsonization and C2 deficiency in atopic patients.

Clinical and experimental immunology ·Vol. 34 ·No. 2 ·1978-11-00 ·Pages 253-9

Turner MW, Mowbray JF, Harvey BA, Brostoff J, Wells RS, Soothill JF

Abstract

Twenty-seven per cent of atopic patients initially presenting with infantile eczema or hay fever were defective for yeast opsonization and 18% had low levels of C2; these deficiencies were mutually exclusive, suggesting that they are primary. Both defects were associated with each of four different atopic syndromes, some of which were related to certain HLA haplotypes.

MeSH Terms
Adolescent Adult Child Child, Preschool Complement C2/deficiency HLA Antigens/immunology Humans Hypersensitivity, Immediate/immunology Infant Neutrophils/immunology Opsonin Proteins/immunology Yeasts/immunology
Chemicals
Complement C2 HLA Antigens Opsonin Proteins
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Turner M W
Mowbray J F
Harvey B A
Brostoff J
Wells R S
Soothill J F
References (10)
10 references, click to expand
  1. Complexed IgE in atopy.
    Lancet. 1977 Oct 8;2(8041):741-2 PMID: 71544
  2. A new semiquantitative radiometric opsonin assay. Selective measurement of opsonizing capacity of the alternative pathway.
    Immunology. 1978 Apr;34(4):689-94 PMID: 363601
  3. A defect of the alternative pathway of complement.
    Clin Exp Immunol. 1977 Jan;27(1):30-3 PMID: 321158
  4. HLA in eczema and hay fever.
    Clin Exp Immunol. 1977 Jan;27(1):43-7 PMID: 849649
  5. Inherited deficiency of the second component of complement. Rheumatic disease associations.
    J Clin Invest. 1976 Oct;58(4):853-61 PMID: 965492
  6. Rat IgE production. II. Primary and booster reaginic antibody responses following intradermal or oral immunization.
    Immunology. 1976 May;30(5):671-7 PMID: 179938
  7. Immunochemical quantitation of antigens by single radial immunodiffusion.
    Immunochemistry. 1965 Sep;2(3):235-54 PMID: 4956917
  8. Hereditary C2 deficiency: diagnosis and HLA gene complex associations.
    J Immunol. 1976 Apr;116(4):1065-70 PMID: 1082903
  9. Defective opsonization. A common immunity deficiency.
    Arch Dis Child. 1976 Feb;51(2):91-9 PMID: 769701
  10. President's address. Some intrinsic and extrinsic factors predisposing to allergy.
    Proc R Soc Med. 1976 Jun;69(6):439-42 PMID: 959217
Article Info
Journal
Clinical and experimental immunology
Abbr.
Clin Exp Immunol
ISSN
0009-9104
Published
1978-11-00
Pages
253-9
Language
English
Region
England
NLM ID
0057202
PMCID
PMC1537493
Subset
IM
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