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PMID: 7388902 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Association of thy-1 cell surface differentiation antigen with certain connective tissues in vivo.

Cell and tissue research ·Vol. 206 ·No. 3 ·1980-00-00 ·Pages 459-75

Morris RJ, Ritter MA

Abstract

The cell surface differentiation antigen, Thy-1, has been demonstrated by immunofluorescence to be associated with some collagen-based connective tissue. In the rat, the basement membrane of kidney collecting tubules of certain blood vessels, reticulin of the lamina propria, loose connective tissue in the dermis, and collagen fibres within certain nerve cell tumours, bear the antigen. Other, apparently similar, connective tissue (especially that of muscle and liver) lacked Thy-1. In the mouse, only the connective tissue of the skin was found to bear the antigen. The possible origin of this extracellular Thy-1, and its implications for the function of the molecule, are discussed.

MeSH Terms
Animals Antigens, Surface/analysis Cell Line Connective Tissue/immunology Eye/immunology Intestine, Small/immunology Kidney/immunology Liver/immunology Lymphoid Tissue/immunology Mice Mice, Inbred Strains Muscles/immunology Neoplasms, Experimental/immunology Rats Rats, Inbred Strains Skin/immunology Tendons/immunology
Chemicals
Antigens, Surface
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Morris R J
Ritter M A
References (40)
40 references, click to expand
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Article Info
Journal
Cell and tissue research
Abbr.
Cell Tissue Res
ISSN
0302-766X
DOI
10.1007/BF00237975
Published
1980-00-00
Pages
459-75
Language
English
Region
Germany
NLM ID
0417625
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00237975 View journal details
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