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PMID: 785217 Published · ppublish English Journal Article

Effect of tra mutations on F factor-specified immunity to lethal zygosis.

Molecular & general genetics : MGG ·Vol. 146 ·No. 2 ·1976-07-23 ·Pages 161-5

Skurray RA, Willetts N, Reeves P

Abstract

Hfr, F+, and F-prime cells are, unlike F- cells, insensitive to an excess of Hfr donor cells, indicating that there is an F factor mediated immunity to lethal zygosis (I1z). Results with Flac episomes carrying traJ, traS or various polar mutations in the tra region indicate that this immunity is independent of surface exclusion, of traJ control, and of all known genes within the tra operon. However, analysis of a series of strains with deletions in the F factor, extending from the right into the tra region, suggests that a gene for immunity to lethal zygosis is located within the tra region. We therefore conclude that I1z is genetically complex, and present a hypothesis to account for these results.

MeSH Terms
Cell Membrane Conjugation, Genetic Escherichia coli F Factor Genes, Lethal Mutation Operon
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Skurray R A
Willetts N
Reeves P
References (19)
19 references, click to expand
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Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
Published
1976-07-23
Pages
161-5
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
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