Iron absorption in normal subjects and patients with idiopathic haemochromatosis: relationship with serum ferritin concentration.

Gut ·Vol. 16 ·No. 3 ·1975-03-00 ·Pages 188-92

Walters GO, Jacobs A, Worwood M, Trevett D, Thomson W

Abstract

In 52 normal subjects there was an inverse relationship between serum ferritin concentration and iron absorption. In 21 measurements in 15 patients with idiopathic haemochromatosis there was a similar inverse relationship but absorption was higher in relation to iron stores at all levels. Haemochromatotic patients with normal serum ferritin levels had abnormally high values for desferrioxamine chelatable iron and there was no correlation between chelatable iron and iron absorption.

MeSH Terms

Adult Deferoxamine Female Ferritins/blood Hemochromatosis/blood,metabolism Hemoglobins/analysis Humans Intestinal Absorption Iron/blood,metabolism Iron Radioisotopes Male Sex Factors Transferrin/analysis Whole-Body Counting

Chemicals

Hemoglobins Iron Radioisotopes Transferrin Ferritins Iron Deferoxamine

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Walters G O

Jacobs A

Worwood M

Trevett D

Thomson W

References (20)

20 references, click to expand

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Article Info

Journal

Gut

Abbr.

Gut

ISSN

0017-5749

DOI

10.1136/gut.16.3.188

Published

1975-03-00

Pages

188-92

Language

English

Region

England

NLM ID

2985108R

PMCID

PMC1410965

Subset

External Links

PubMed source DOI: 10.1136/gut.16.3.188 PMC Full Text View journal details

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Iron absorption in normal subjects and patients with idiopathic haemochromatosis: relationship with serum ferritin concentration.

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