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PMID: 8369439 Published · ppublish English Journal Article

Cellular motions and thermal fluctuations: the Brownian ratchet.

Biophysical journal ·Vol. 65 ·No. 1 ·1993-07-00 ·Pages 316-24

Peskin CS, Odell GM, Oster GF

Abstract

We present here a model for how chemical reactions generate protrusive forces by rectifying Brownian motion. This sort of energy transduction drives a number of intracellular processes, including filopodial protrusion, propulsion of the bacterium Listeria, and protein translocation.

MeSH Terms
Biological Transport, Active Biomechanical Phenomena Biophysical Phenomena Biophysics Cell Movement/physiology Energy Metabolism Listeria monocytogenes/physiology Membrane Proteins/physiology Models, Biological Polymers/metabolism Thermodynamics
Chemicals
Membrane Proteins Polymers
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Peskin C S
Courant Institute of Mathematical Sciences, New York, New York 10012.
Odell G M
Oster G F
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Article Info
Journal
Biophysical journal
Abbr.
Biophys J
ISSN
0006-3495
DOI
10.1016/S0006-3495(93)81035-X
Published
1993-07-00
Pages
316-24
Language
English
Region
United States
NLM ID
0370626
PMCID
PMC1225726
Subset
IM
External Links
PubMed source DOI: 10.1016/S0006-3495(93)81035-X PMC Full Text View journal details
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