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PMID: 8423163 Published · ppublish English Journal Article

The inherent DNase of pyocin AP41 causes breakdown of chromosomal DNA.

Journal of bacteriology ·Vol. 175 ·No. 3 ·1993-02-00 ·Pages 912-5

Sano Y

Abstract

Pyocin AP41 degrades the chromosomal DNA in sensitive strains of Pseudomonas aeruginosa but has little effect on RNA, protein, and lipid syntheses. In vitro experiments showed that the carboxyl-terminal part of the large subunit of pyocin AP41 carries an inherent DNase that is responsible for its killing action.

MeSH Terms
Amino Acid Sequence Chromosomes, Bacterial/metabolism DNA, Bacterial/metabolism Deoxyribonucleases/metabolism Molecular Sequence Data Peptide Fragments/metabolism Pseudomonas aeruginosa/metabolism Pyocins/chemistry,metabolism Trypsin
Chemicals
DNA, Bacterial Peptide Fragments Pyocins Deoxyribonucleases Trypsin
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Sano Y
Department of Molecular Biology, Mitsubishi Kasei Institute of Life Sciences, Tokyo, Japan.
References (11)
11 references, click to expand
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    J Bacteriol. 1984 May;158(2):562-70 PMID: 6202673
  10. Comparative nucleotide sequences encoding the immunity proteins and the carboxyl-terminal peptides of colicins E2 and E3.
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.175.3.912-915.1993
Published
1993-02-00
Pages
912-5
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC196246
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.175.3.912-915.1993 PMC Full Text View journal details
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