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PMID: 8430085 Published · ppublish English Journal Article

Glucokinase, glucose sensing, and diabetes.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 90 ·No. 3 ·1993-02-01 ·Pages 784-5

Mueckler M

Abstract

暂无摘要

MeSH Terms
Diabetes Mellitus/enzymology,etiology Diabetes Mellitus, Type 2/enzymology,etiology Glucokinase/metabolism Glucose/metabolism Humans Islets of Langerhans/metabolism Signal Transduction
Chemicals
Glucokinase Glucose
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Mueckler M
Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO 63110.
References (14)
14 references, click to expand
  1. Regulation of insulin secretion studied with pieces of rabbit pancreas incubated in vitro.
    Biochem J. 1964 Oct;93(1):66-78 PMID: 5320084
  2. Metabolism of glucose in the islets of Langerhans.
    J Biol Chem. 1968 May 25;243(10):2730-6 PMID: 4870741
  3. Pancreatic islet glucose metabolism and regulation of insulin secretion.
    Diabetes Metab Rev. 1986;2(3-4):163-214 PMID: 2943567
  4. The amino acid sequence of rat liver glucokinase deduced from cloned cDNA.
    J Biol Chem. 1989 Jan 5;264(1):363-9 PMID: 2909525
  5. Rat glucokinase gene: structure and regulation by insulin.
    Proc Natl Acad Sci U S A. 1989 Jul;86(13):4838-42 PMID: 2662183
  6. Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus.
    Nature. 1992 Mar 12;356(6365):162-4 PMID: 1545870
  7. EFFECTS OF CARBOHYDRATES ON SECRETION OF INSULIN FROM ISOLATED RAT PANCREAS.
    Am J Physiol. 1963 Oct;205:638-44 PMID: 14060797
  8. Linkage of type 2 diabetes to the glucokinase gene.
    Lancet. 1992 May 30;339(8805):1307-10 PMID: 1349989
  9. Human islet glucokinase gene. Isolation and sequence analysis of full-length cDNA.
    Diabetes. 1992 Jul;41(7):807-11 PMID: 1612194
  10. Glucokinase gene is genetic marker for NIDDM in American blacks.
    Diabetes. 1992 Jul;41(7):843-9 PMID: 1612198
  11. Human glucokinase gene: isolation, structural characterization, and identification of a microsatellite repeat polymorphism.
    Mol Endocrinol. 1992 Jul;6(7):1070-81 PMID: 1354840
  12. Linkage analysis of glucokinase gene with NIDDM in Caucasian pedigrees.
    Diabetes. 1992 Nov;41(11):1496-500 PMID: 1397724
  13. Expression of yeast hexokinase in pancreatic beta cells of transgenic mice reduces blood glucose, enhances insulin secretion, and decreases diabetes.
    Proc Natl Acad Sci U S A. 1992 Dec 15;89(24):12038-42 PMID: 1465437
  14. Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus.
    Nature. 1992 Apr 23;356(6371):721-2 PMID: 1570017
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.90.3.784
Published
1993-02-01
Pages
784-5
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC45753
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.90.3.784 PMC Full Text View journal details
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