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PMID: 8432713 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Function of periplasmic copper-zinc superoxide dismutase in Caulobacter crescentus.

Journal of bacteriology ·Vol. 175 ·No. 4 ·1993-02-00 ·Pages 1198-202

Steinman HM

Abstract

Caulobacter crescentus is one of a small number of bacterial species that contain a periplasmic copper-zinc superoxide dismutase (CuZnSOD). A C. crescentus mutant, with the CuZnSOD gene interrupted by a promoterless cat gene, was constructed and characterized to analyze CuZnSOD function. Periplasmic SOD does not protect against oxyradical damage in the cytosol or play a major role in maintaining the integrity of the cell envelope. Studies of the effect of sodium citrate on plating efficiency suggest that CuZnSOD protects a periplasmic or membrane function(s) requiring magnesium or calcium.

Related Genes
sodC
MeSH Terms
Cations, Divalent Caulobacter/drug effects,enzymology,genetics Cell Membrane/physiology Chlorpromazine/pharmacology Citrates/pharmacology Genes, Bacterial Mutagenesis, Insertional Oxidation-Reduction Paraquat/pharmacology Superoxide Dismutase/metabolism
Chemicals
Cations, Divalent Citrates Superoxide Dismutase Paraquat Chlorpromazine
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Steinman H M
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461.
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30 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.175.4.1198-1202.1993
Published
1993-02-00
Pages
1198-202
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC193039
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.175.4.1198-1202.1993 PMC Full Text View journal details
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