Home LiteratureArticle Details
PMID: 8436278 Published · ppublish English Comparative Study Journal Article Research Support, U.S. Gov't, Non-P.H.S.

DNA sequence variation at the period locus within and among species of the Drosophila melanogaster complex.

Genetics ·Vol. 133 ·No. 2 ·1993-02-00 ·Pages 375-87

Kliman RM, Hey J

Abstract

A 1.9-kilobase region of the period locus was sequenced in six individuals of Drosophila melanogaster and from six individuals of each of three sibling species: Drosophila simulans, Drosophila sechellia and Drosophila mauritiana. Extensive genealogical analysis of 174 polymorphic sites reveals a complex history. It appears that D. simulans, as a large population still segregating very old lineages, gave rise to the island species D. mauritiana and D. sechellia. Rather than considering these speciation events as having produced "sister" taxa, it seems more appropriate to consider D. simulans a parent species to D. sechellia and D. mauritiana. The order, in time, of these two phylogenetic events remains unclear. D. mauritiana supports a large number of polymorphisms, many of which are shared with D. simulans, and so appears to have begun and persisted as a large population. In contrast, D. sechellia has very little variation and seems to have experienced a severe population bottleneck. Alternatively, the low variation in D. sechellia could be due to recent directional selection and genetic hitchhiking at or near the per locus.

Related Genes
per
MeSH Terms
Animals Base Sequence DNA/genetics Drosophila/genetics Drosophila melanogaster/genetics Genes, Insect Genetic Variation Molecular Sequence Data Phylogeny Polymerase Chain Reaction Polymorphism, Genetic Recombination, Genetic Selection, Genetic Sequence Homology, Nucleic Acid Species Specificity
Chemicals
DNA
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Kliman R M
Department of Biological Sciences, Nelson Laboratories, Rutgers University, Piscataway, New Jersey 08855-1059.
Hey J
References (33)
33 references, click to expand
  1. Rates and patterns of scnDNA and mtDNA divergence within the Drosophila melanogaster subgroup.
    Genetics. 1988 Apr;118(4):671-83 PMID: 2896615
  2. Restriction-map variation in the Notch region of Drosophila melanogaster.
    Mol Biol Evol. 1988 Jan;5(1):30-40 PMID: 2833676
  3. Molecular and phenotypic variation of the white locus region in Drosophila melanogaster.
    Genetics. 1988 Sep;120(1):199-212 PMID: 2906026
  4. Production of single-stranded DNA templates by exonuclease digestion following the polymerase chain reaction.
    Nucleic Acids Res. 1989 Jul 25;17(14):5865 PMID: 2548171
  5. Restriction-map variation with the yellow-achaete-scute region in five populations of Drosophila melanogaster.
    Mol Biol Evol. 1989 Sep;6(5):492-502 PMID: 2552253
  6. Low allozyme and mtDNA variability in the island endemic species Drosophila sechellia (D. melanogaster complex).
    Experientia. 1990 Jan 15;46(1):101-4 PMID: 2153569
  7. The "hitchhiking effect" revisited.
    Genetics. 1989 Dec;123(4):887-99 PMID: 2612899
  8. Restriction-map variation associated with the G6PD polymorphism in natural populations of Drosophila melanogaster.
    Mol Biol Evol. 1989 Jul;6(4):384-97 PMID: 2575699
  9. Electrolyte gradient gels for DNA sequencing.
    Biotechniques. 1988 Nov-Dec;6(10):942-4 PMID: 3273397
  10. Molecular evolution in the Drosophila yakuba period locus.
    J Mol Evol. 1990 Nov;31(5):389-401 PMID: 1702156
  11. Molecular transfer of a species-specific behavior from Drosophila simulans to Drosophila melanogaster.
    Science. 1991 Mar 1;251(4997):1082-5 PMID: 1900131
  12. Host-plant specialization in the Drosophila melanogaster species complex: a physiological, behavioral, and genetical analysis.
    Proc Natl Acad Sci U S A. 1991 Mar 1;88(5):1835-9 PMID: 1900368
  13. Inferring the evolutionary histories of the Adh and Adh-dup loci in Drosophila melanogaster from patterns of polymorphism and divergence.
    Genetics. 1991 Mar;127(3):565-82 PMID: 1673107
  14. Adaptive protein evolution at the Adh locus in Drosophila.
    Nature. 1991 Jun 20;351(6328):652-4 PMID: 1904993
  15. The structure of genealogies and the distribution of fixed differences between DNA sequence samples from natural populations.
    Genetics. 1991 Aug;128(4):831-40 PMID: 1916247
  16. The number of heterozygous nucleotide sites maintained in a finite population due to steady flux of mutations.
    Genetics. 1969 Apr;61(4):893-903 PMID: 5364968
  17. The hitch-hiking effect of a favourable gene.
    Genet Res. 1974 Feb;23(1):23-35 PMID: 4407212
  18. On the number of segregating sites in genetical models without recombination.
    Theor Popul Biol. 1975 Apr;7(2):256-76 PMID: 1145509
  19. Mathematical model for studying genetic variation in terms of restriction endonucleases.
    Proc Natl Acad Sci U S A. 1979 Oct;76(10):5269-73 PMID: 291943
  20. The theory of speciation via the founder principle.
    Genetics. 1980 Apr;94(4):1011-38 PMID: 6777243
  21. Estimation of evolutionary distances between homologous nucleotide sequences.
    Proc Natl Acad Sci U S A. 1981 Jan;78(1):454-8 PMID: 6165991
  22. Expected linkage disequilibrium for a neutral locus linked to a chromosomal arrangement.
    Genetics. 1983 Mar;103(3):545-55 PMID: 6404695
  23. A transposable element inserted just 5' to a Drosophila glue protein gene alters gene expression and chromatin structure.
    Cell. 1983 Aug;34(1):75-84 PMID: 6309414
  24. Properties of a neutral allele model with intragenic recombination.
    Theor Popul Biol. 1983 Apr;23(2):183-201 PMID: 6612631
  25. Conservation and change in the DNA sequences coding for alcohol dehydrogenase in sibling species of Drosophila.
    Nature. 1984 May 31-Jun 6;309(5967):425-30 PMID: 6427630
  26. [Effects of long-term administration of Tegafur on patients with relapsing advanced carcinoma (stage D) of the prostate].
    Hinyokika Kiyo. 1983 Jan;29(1):105-11 PMID: 6428191
  27. Nucleotide sequence comparison of the Adh gene in three drosophilids.
    J Mol Evol. 1984;20(1):31-7 PMID: 6429340
  28. Evidence for higher rates of nucleotide substitution in rodents than in man.
    Proc Natl Acad Sci U S A. 1985 Mar;82(6):1741-5 PMID: 3856856
  29. Statistical properties of the number of recombination events in the history of a sample of DNA sequences.
    Genetics. 1985 Sep;111(1):147-64 PMID: 4029609
  30. Molecular population genetics of the alcohol dehydrogenase gene region of Drosophila melanogaster.
    Genetics. 1986 Dec;114(4):1165-90 PMID: 3026893
  31. A family of unusually spliced biologically active transcripts encoded by a Drosophila clock gene.
    Nature. 1987 Mar 5-11;326(6108):42-7 PMID: 3102970
  32. A test of neutral molecular evolution based on nucleotide data.
    Genetics. 1987 May;116(1):153-9 PMID: 3110004
  33. The rosy region of Drosophila melanogaster and Drosophila simulans. I. Contrasting levels of naturally occurring DNA restriction map variation and divergence.
    Genetics. 1988 Aug;119(4):875-88 PMID: 2900794
Article Info
Journal
Genetics
Abbr.
Genetics
ISSN
0016-6731
DOI
10.1093/genetics/133.2.375
Published
1993-02-00
Pages
375-87
Language
English
Region
United States
NLM ID
0374636
PMCID
PMC1205326
Subset
IM
Databases
GENBANK
L07811, L07812, L07813, L07814, L07815, L07816, L07817, L07818, L07819, L07820, L07821, L07822, L07823, L07824, L07825, L07826, L07827, L07828, L07829, L07830, L07831, L07832
External Links
PubMed source DOI: 10.1093/genetics/133.2.375 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2