Home LiteratureArticle Details

PMID: 8913754 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

The speciation history of Drosophila pseudoobscura and close relatives: inferences from DNA sequence variation at the period locus.

Genetics ·Vol. 144 ·No. 3 ·1996-11-00 ·Pages 1113-26

Wang RL, Hey J

Abstract

Thirty-five period locus sequences from Drosophila pseudoobscura and its siblings species, D. p. bogotana, D. persimilis, and D. miranda, were studied. A large amount of variation was found within D. pseudoobscura and D. persimilis, consistent with histories of large effective population sizes. D. p. bogotana, however, has a severe reduction in diversity. Combined analysis of per with two other loci, in both D. p. bogotana and D. pseudoobscura, strongly suggest this reduction is due to recent directional selection at or near per within D. p. bogotana. Since D. p. bogotana is highly variable and shares variation with D. pseudoobscura at other loci, the low level of variation at per within D. p. bogotana can not be explained by a small effective population size or by speciation via founder event. Both D. pseudoobscura and D. persimilis have considerable intraspecific gene flow. A large portion of one D. persimilis sequence appears to have arisen via introgression from D. pseudoobscura. The time of this event appears to be well after the initial separation of these two species. The estimated times since speciation are one mya for D. pseudoobscura and D. persimilis and 2 mya since the formation of D. miranda.

MeSH Terms

Amino Acid Sequence Animals Base Sequence DNA/analysis Drosophila/classification,genetics Drosophila Proteins Genetic Variation Male Molecular Sequence Data Nuclear Proteins/genetics Period Circadian Proteins Recombination, Genetic Selection, Genetic Time Factors

Chemicals

Drosophila Proteins Nuclear Proteins PER protein, Drosophila Period Circadian Proteins DNA

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Wang R L

Department of Biological Sciences, Rutgers University, Piscataway, New Jersey 08855-1059, USA.

Hey J

References (35)

35 references, click to expand

Statistical method for testing the neutral mutation hypothesis by DNA polymorphism.
Genetics. 1989 Nov;123(3):585-95 PMID: 2513255
The hitch-hiking effect of a favourable gene.
Genet Res. 1974 Feb;23(1):23-35 PMID: 4407212
Behaviour modification by in vitro mutagenesis of a variable region within the period gene of Drosophila.
Nature. 1987 Apr 23-29;326(6115):765-9 PMID: 3106823
Reproductive isolation and the period gene of Drosophila.
Mol Ecol. 1994 Dec;3(6):595-9 PMID: 7834109
Circadian rhythm mutations in Drosophila melanogaster affect short-term fluctuations in the male's courtship song.
Proc Natl Acad Sci U S A. 1980 Nov;77(11):6729-33 PMID: 6779281
Phase shifting of the circadian clock by induction of the Drosophila period protein.
Science. 1994 Jan 14;263(5144):237-40 PMID: 8284676
Estimating the recombination parameter of a finite population model without selection.
Genet Res. 1987 Dec;50(3):245-50 PMID: 3443297
Adaptive protein evolution at the Adh locus in Drosophila.
Nature. 1991 Jun 20;351(6328):652-4 PMID: 1904993
Genetics of natural populations. XXXI. Genetics of an isolated marginal population of Drosophila pseudoobscura.
Genetics. 1963 Jan;48:91-103 PMID: 14028271
Statistical properties of the number of recombination events in the history of a sample of DNA sequences.
Genetics. 1985 Sep;111(1):147-64 PMID: 4029609
Restriction-map variation in the alcohol dehydrogenase region of Drosophila pseudoobscura.
Mol Biol Evol. 1987 May;4(3):254-65 PMID: 2833670
Molecular evolution of inversions in Drosophila pseudoobscura: the amylase gene region.
Proc Natl Acad Sci U S A. 1991 Jan 1;88(1):305-9 PMID: 1702542
Nucleotide sequence analysis of Adh genes estimates the time of geographic isolation of the Bogota population of Drosophila pseudoobscura.
Proc Natl Acad Sci U S A. 1991 Jul 15;88(14):6097-101 PMID: 2068088
Clock mutants of Drosophila melanogaster.
Proc Natl Acad Sci U S A. 1971 Sep;68(9):2112-6 PMID: 5002428
Gene genealogy and variance of interpopulational nucleotide differences.
Genetics. 1985 Jun;110(2):325-44 PMID: 4007484
Molecular transfer of a species-specific behavior from Drosophila simulans to Drosophila melanogaster.
Science. 1991 Mar 1;251(4997):1082-5 PMID: 1900131
DNA sequence variation at the period locus within and among species of the Drosophila melanogaster complex.
Genetics. 1993 Feb;133(2):375-87 PMID: 8436278
Nucleotide polymorphism at the alcohol dehydrogenase locus of Drosophila melanogaster.
Nature. 1983 Aug 4-10;304(5925):412-7 PMID: 6410283
The coalescent process in models with selection.
Genetics. 1988 Nov;120(3):819-29 PMID: 3066685
Estimates of gene flow in Drosophila pseudoobscura determined from nucleotide sequence analysis of the alcohol dehydrogenase region.
Genetics. 1992 Oct;132(2):471-80 PMID: 1427038
Interspecific cytoplasmic gene flow in the absence of nuclear gene flow: evidence from Drosophila.
Proc Natl Acad Sci U S A. 1983 Jan;80(2):492-5 PMID: 6300849
Conservation and change in the DNA sequences coding for alcohol dehydrogenase in sibling species of Drosophila.
Nature. 1984 May 31-Jun 6;309(5967):425-30 PMID: 6427630
Inbreeding coefficients and coalescence times.
Genet Res. 1991 Oct;58(2):167-75 PMID: 1765264
The molecular biology of circadian rhythms.
Neuron. 1989 Oct;3(4):387-98 PMID: 2701842
Properties of a neutral allele model with intragenic recombination.
Theor Popul Biol. 1983 Apr;23(2):183-201 PMID: 6612631
Interspecific comparison of the period gene of Drosophila reveals large blocks of non-conserved coding DNA.
EMBO J. 1988 Dec 1;7(12):3929-37 PMID: 3208754
The molecular ethology of the period gene in Drosophila.
Behav Genet. 1990 Mar;20(2):191-211 PMID: 2112912
Mitochondrial DNA variation in Drosophila pseudoobscura and related species in Pacific northwest populations.
Can J Genet Cytol. 1985 Jun;27(3):357-64 PMID: 3880378
Drosophila Miranda, a New Species.
Genetics. 1935 Jul;20(4):377-91 PMID: 17246767
Genetics of postmating reproductive isolation in animals.
Annu Rev Genet. 1994;28:283-308 PMID: 7893128
The role of molecular genetics in speciation studies.
EXS. 1994;69:455-77 PMID: 7994119
A molecular approach to the study of genic heterozygosity in natural populations. 3. Direct evidence of coadaptation in gene arrangements of Drosophila.
Proc Natl Acad Sci U S A. 1968 Feb;59(2):398-405 PMID: 5238972
A test of neutral molecular evolution based on nucleotide data.
Genetics. 1987 May;116(1):153-9 PMID: 3110004
Nucleotide polymorphism at the xanthine dehydrogenase locus in Drosophila pseudoobscura.
Mol Biol Evol. 1992 Jan;9(1):56-69 PMID: 1552841
Population genetics and phylogenetics of DNA sequence variation at multiple loci within the Drosophila melanogaster species complex.
Mol Biol Evol. 1993 Jul;10(4):804-22 PMID: 8355601

Article Info

Journal

Genetics

Abbr.

Genetics

ISSN

0016-6731

DOI

10.1093/genetics/144.3.1113

Published

1996-11-00

Pages

1113-26

Language

English

Region

United States

NLM ID

0374636

PMCID

PMC1207605

Subset

Databases

GENBANK

L81261, L81262, L81263, L81264, L81265, L81266, L81267, L81268, L81269, L81270, L81271, L81272, L81273, L81274, L81275, L81276, L81277, L81278, L81279, L81280, L81281, L81282, L81283, L81284, L81285, L81286, L81287, L81288, L81289, L81290

External Links

PubMed source DOI: 10.1093/genetics/144.3.1113 PMC Full Text View journal details

Analysis Services

The speciation history of Drosophila pseudoobscura and close relatives: inferences from DNA sequence variation at the period locus.

Contact

WeChat Official Account