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PMID: 994300 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Infectious, linear, unintegrated DNA of Moloney murine leukemia virus.

Journal of virology ·Vol. 20 ·No. 3 ·1976-12-00 ·Pages 621-6

Smotkin D, Yoshimura FK, Weinberg RA

Abstract

A closed circular, double-stranded infectious DNA of Moloney leukemia virus has been described previously. The present report characterizes a second type of infectious, unintegrated viral DNA which is linear, largely double stranded, and of mass comparable to that of the closed circular viral DNA. The linear form is of nonpermuted sequence, and SalI endonuclease cleaves at one site 45% from one end.

MeSH Terms
DNA, Circular/analysis DNA, Viral/analysis Electrophoresis, Agar Gel Endonucleases Moloney murine leukemia virus/analysis Nucleic Acid Conformation Nucleic Acid Hybridization
Chemicals
DNA, Circular DNA, Viral Endonucleases
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Smotkin D
Yoshimura F K
Weinberg R A
References (13)
13 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.20.3.621-626.1976
Published
1976-12-00
Pages
621-6
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC355039
Subset
IM
External Links
PubMed source DOI: 10.1128/JVI.20.3.621-626.1976 PMC Full Text View journal details
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