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JAK2V617F mutant HSC microarray

样本量:9 物种:Mus musculus 类型:transcription profiling by array 2018年8月6日

...JAK2V617F is found in majority of patients with myeloproliferative neoplasm. While heterozygous JAK2V617F induced an ET-...

Hepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress...

样本量:24 物种:Mus musculus 类型:transcription profiling by array 2016年10月1日

...JAK2 (JAK2Δhep) and compared them to GHtgSTAT5Δhep mice. We show that JAK2 deficiency in the GHtg background resulted in...

The essential role of PBX1, a stem cell reprogramming factor, in ovarian canc...

样本量:2 物种:Homo sapiens 类型:transcription profiling by array 2016年7月25日

...JAK2 inhibitor potently sensitizes platinum-resistant cells to carboplatin and suppresses their growth in vivo. These fi...

Next Generation Sequencing of megakaryocyte-erythrocyte progenitor cells (MEP...

样本量:29 物种:Mus musculus 类型:RNA-seq of coding RNA 2016年6月24日

...JAK2V617F, SclCre; JAK2V617F;Ezh2+/-, SclCre; JAK2V617F;Ezh2-/-) 10 weeks after tamoxifen injection. Our study represent...

Loss of Ezh2 synergizes with JAK2-V617F in initiating myeloproliferative neop...

样本量:64 物种:Mus musculus 类型:RNA-seq of coding RNA 2016年6月24日

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

Next Generation Sequencing of long-term hematopoietic cells (LT-HSCs) with or...

样本量:35 物种:Mus musculus 类型:RNA-seq of coding RNA 2016年6月24日

...JAK2V617F, SclCre; JAK2V617F;Ezh2+/-, SclCre; JAK2V617F;Ezh2-/-) 10 weeks after tamoxifen injection. Our study represent...

Loss of p53 shifts transient to persistent Jak2/Stat3 activation

样本量:8 物种:Mus musculus 类型:transcription profiling by array 2016年6月1日

Comparison of persistent Stat3, transient Stat3, and Stat3 deficient murine cells

Epo-Induced Erythroid Maturation Is Dependent on Plcγ1 Signaling

样本量:6 物种:Mus musculus 类型:methylation profiling by high through... 2015年12月31日

...Jak2 tyrosine-kinase and Stat5a/b as a central pathway. Here, we demonstrate that phospholipase C gamma 1 (Plcγ1) is act...

Gene expression data of diagnostic childhood T-ALL samples and human thymocyt...

样本量:10 物种:Homo sapiens 类型:transcription profiling by array 2015年11月20日

...JAK2;Ltbr–/– mice presented significantly less leukemic thymocytes than TEL-JAK2;Ltbr+/+ mice. Together, these data indi...

Effect of a JAK inhibitor on gene expression of HUT78 cell line

样本量:18 物种:Homo sapiens 类型:transcription profiling by array 2015年10月31日

...JAK2 and JAK3 genes in a series of human CTCL lesions and cell lines using next-generation sequencing (NGS). We found th...

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