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Callistephus A from Callistephus chinensis alleviates DSS-induced ulcerative ...

Yang(N),Ye(M),Wang(H),Liang(Y),Huang(K),Zh... J Ethnopharmacol 2027-01-10

...JAK2 and STAT1, suppressing JAK2/STAT1 pathway phosphorylation to under 0.3 times the DSS group level, confirmed by inhi...

Xuefu Zhuyu decoction attenuates thoracic aortic dissection by regulating VSM...

Cheng-Wen(L),Rong(G),Yi-Fan(J),Shou-Jia(W)... J Ethnopharmacol 2026-05-10

...JAK2/STAT3/HIF-1α axis as core regulatory axis. XFZY dose-dependently inhibited JAK2/STAT3 activation and HIF-1α express...

Abrogation of PDE7A ameliorates alveolar epithelial EMT-Driven pulmonary fibr...

Guo(J),Zhou(J),Cheng(A),Hu(W),Qi(T),Zhao(D... Biochem Pharmacol 2026-05-00

...JAK2/STAT3 signaling pathway activation. This inhibition suppressed EMT, inflammatory factor release, and collagen depos...

Sinomenine treats Rheumatoid Arthritis by regulating IL-6 Gene Promoter Methy...

Luo(JF),Yu(Y),Yao(YD),Zhang(C),Liu(JX),Lio... Phytomedicine 2026-04-00

...JAK2), and bisulfite sequencing (IL-6 promoter methylation in THP-1 cells) were performed. A collagen-induced arthritis ...

Activation of M1mAChR's improves spatial learning and memory deficits in rats...

Huang(Q),Hu(C),Liu(H),Liu(C),Liu(X),Xu(Z),... Sci Rep 2026-02-13

...JAK2/STAT3 signaling (abolished by AG490). These findings support functional crosstalk between M1mAChR and JAK2/STAT3 in...

Mechanism by which Icariin suppresses pulmonary metastasis in triple-negative...

Xiao(Z),Yang(Z),Li(X),Chen(X),Li(J),He(Y),... Cancer Cell Int 2026-02-12

...JAK2/STAT3 signaling axis by downregulating spindle apparatus coiled-coil protein 1 (SPDL1). These experimental data con...

Echinacea Purpurea Polysaccharides Alleviate DSS-Induced Colitis in Rats by R...

Liu(C),Lin(Y),Du(X),Mei(J),Xi(K),Gao(Y),Li... Foods 2026-01-23

...JAK2/STAT3 and TRAF6/NF-κB signaling pathways, with its therapeutic mechanism intricately linked to the microbiota-metab...

Mechanism of RBM15 in Regulating PD-L1-Mediated Immune Escape in Ovarian Canc...

Zhang(C),Feng(T),Wang(H),He(D),Wang(X),Ni(... Arch Immunol Ther Exp (Wars... 2026-01-01

...JAK2, p-STAT3, and p-STAT5 was investigated. The bindings of circFGFR3 to EIF4A3 and EIF4A3 to JAK2, STAT3, or STAT5 wer...

In-silico target prediction and pathway analysis of propranolol as a potentia...

Ahmad(I),Khan(SA),Abu Bakar(M),Shakoor(A),... PLoS One None

...JAK2, ERBB2, PARP1, CDK4, CDK2, CHEK1) with degree centrality values exceeding 23.2, more than twice the network average...

Complete remission of relapsed ATXN2L::JAK2 fusion positive anaplastic large ...

Cohen(T),Zhou(T),Edema(U),Pandit-Taskar(N)... NPJ Precis Oncol 2026-02-14

...JAK2 fusion, who achieved complete remission with ruxolitinib monotherapy. Consolidative allogeneic hematopoietic stem c...

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