Guo(WW),Dongzhi(C),Ma(T),Zhang(M),Gao(M),L... Int J Biol Sci None

...CCT2) in HCC remains unclear. This study aimed to elucidate the function of CCT2 in HCC tumorigenesis. Bioinformatics an...

Dialynaki(D),Huang(Y),Klionsky(DJ) Autophagy 2026-08-26

...Cct2 and the polyglutamine repeats of the HTT (huntingtin) protein (polyQ-HTT). Notably, even though Cct2 and polyQ-HTT ...

Abou Al-Saud(S) Int J Mol Sci 2026-07-11

...CCT2/CCT5, PSMA3, and stress-responsive STAT3 further link metabolic stress to proteotoxic injury. Epigenetic mechanisms...

Gu(L),Li(S),Tang(Y),Ji(L) J Gastroenterol Hepatol 2026-08-12

...CCT2 as a core gene of CRC. Analysis of public datasets revealed a significant increase in CCT2 expression in CRC tissue...

Du(Z),Zhang(X),Zhang(Q),Li(J),Cao(Z),Gao(G... Genome Res 2026-08-03

...CCT2 in primordial germ cells (PGCs). Additionally, it identifies unexplored species-specific genes PRICKLE4 and CTSV in...

Wang(QH),Xie(S),Yang(KH),Guo(YX),Huang(HY)... J Neurosci 2026-01-07

...Cct2 mRNA and upregulated CCT2 protein expression. Pharmacological inhibition of H3K18la activity by injection of 2-DG o...

Dong(T),Jiao(X),Wang(H),Gao(Y),Xu(Y),Li(H)... Proc Natl Acad Sci U S A 2026-01-27

...CCT2) to degrade misfolded vimentin aggregates. Pathologically, external profibrotic stimuli trigger calcium transients ...

Zhang(X),Zhou(Y),Yin(H) ACS Chem Biol 2026-05-15

...CCT2 as a previously unappreciated cGAS-associated factor. Functional analyses demonstrated that CCT2 attenuates cGAS-ST...

Wang(H),Chen(X),Liu(Y),Wang(S),Xiang(Q),Zh... Sci Rep 2026-05-07

...CCT2 promotes tumor growth. Knockdown of CCT2 expression via gene silencing markedly activated the p53 signaling pathway...

Li(C),Yang(L),Zhang(Y),Zhao(B),Qu(H) Oncol Rep 2026-05-00

...CCT2) participates in the development of numerous types of liver disease. However, the potential role of CCT2 in regulat...