Lu(L),Shen(Y),Li(X),Zhao(Y),Zhai(X),Cai(M)... Genes Dis 2026-11-00

...CCT2 to neighboring cells, further enhancing chemoresistance. These findings position CCT2 as a key driver of HNSCC prog...

Jen(HW),Ho(HL),Chou(TY) Cells 2026-09-04

...CCT2 depletion exerted the opposite effect by suppressing the DR5-JNK-c-Jun-PD-L1 signaling axis and enhancing T-cell ac...

Dialynaki(D),Huang(Y),Klionsky(DJ) Autophagy 2026-08-26

...Cct2 and the polyglutamine repeats of the HTT (huntingtin) protein (polyQ-HTT). Notably, even though Cct2 and polyQ-HTT ...

Mao(H),Su(C),Han(X),Wang(G) Oncol Lett 2026-10-00

...CCT2) emerging as a key regulator of cisplatin resistance. Single-cell analyses showed that CCT2 was predominantly enric...

Xu(S),Zhang(Y),Li(H),Zhao(S),Dai(X),Xu(Q),... Adv Sci (Weinh) 2026-08-00

...CCT2 transcription is upregulated by the transcription factor Forkhead Box A1 (FOXA1); the CCT2 protein interacts with e...

Li(C),Yang(L),Zhang(Y),Zhao(B),Qu(H) Oncol Rep 2026-05-00

...CCT2) participates in the development of numerous types of liver disease. However, the potential role of CCT2 in regulat...

Zhang(X),Zhou(Y),Yin(H) ACS Chem Biol 2026-05-15

...CCT2 as a previously unappreciated cGAS-associated factor. Functional analyses demonstrated that CCT2 attenuates cGAS-ST...

Wang(H),Chen(X),Liu(Y),Wang(S),Xiang(Q),Zh... Sci Rep 2026-05-07

...CCT2 promotes tumor growth. Knockdown of CCT2 expression via gene silencing markedly activated the p53 signaling pathway...

Guo(WW),Dongzhi(C),Ma(T),Zhang(M),Gao(M),L... Int J Biol Sci None

...CCT2) in HCC remains unclear. This study aimed to elucidate the function of CCT2 in HCC tumorigenesis. Bioinformatics an...

Abou Al-Saud(S) Int J Mol Sci 2026-07-11

...CCT2/CCT5, PSMA3, and stress-responsive STAT3 further link metabolic stress to proteotoxic injury. Epigenetic mechanisms...