...ERCC1 (SMX complex), or (ii) dissolution mediated by BLM-TopoIIIα-RMI1-RMI2 (BTRR complex). To facilitate the biochemica...
...ERCC1)), thereby reversing cisplatin resistance and sensitizing tumor cells to DNA damage. In vivo evaluations in HCC xe...
...ERCC1). Rescue experiments confirmed that the oncogenic effects of hsa_circ_0003472 were mediated through the miR-1253/E...
...Ercc1-/- and wild-type (WT) mice. Ercc1-/- MEFs showed significantly reduced FA levels, while in brains and livers, diff...
...ERCC1) bound to the SLX4 scaffold. A critical step in SMX assembly is the recruitment of MUS81-EME1 to SLX4 in early mit...
...ERCC1/CUL4A CNV gains), and mutational-signature analysis indicated greater MMR- and AID/POLE-associated exposures in th...
...ERCC1 knockout (SMC-KO) mouse model of DNA-damage-driven vascular aging. We performed experiments in the SMC-KO treated ...
...ERCC1± mice via cigarette smoke (CS) exposure. TXL was administrated daily via intragastric gavage. The progression of c...
...ERCC1 expression and specific EXO1 or RPA polymorphisms are associated with enhanced responsiveness to platinum-based ch...
...ERCC1) was further evaluated via cross-species evolutionary conservation and in silico structural modeling of high-risk ...
山东省济南市章丘区文博路2号
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