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Pre-incision structures reveal principles of DNA nucleotide excision repair.

Li(ECL),Kim(J),Brussee(SJ),Sugasawa(K),Lui... Nature 2026-04-00

...ERCC1 subunit of XPF facilitates DNA strand separation and recruitment of RPA to the non-lesion strand. These findings p...

Integrative Transcriptomic Analysis Identifies a Key Candidate Gene Bridging ...

Wang(J),Li(W),Feng(J),Wang(Z) Stem Cells Int None

...ERCC1) was further evaluated via cross-species evolutionary conservation and in silico structural modeling of high-risk ...

CRISPR Screening Identifies SMARCAL1 and MRN as Modulators of WRN Dependency ...

Ma(T),Wu(J),Li(S),Chen(J) Cancer Res 2026-07-22

...ERCC1/XPF, was the principal mediator of cruciform DNA processing following WRN inhibition. Acute disruption of the MRN ...

Dual-site phosphorylation of SLX4 stabilizes the SLX4-MUS81 interface to prom...

Payliss(BJ),Yun(HY),Doshi(S),Lemak(A),Tse(... Nucleic Acids Res 2026-05-05

...ERCC1) bound to the SLX4 scaffold. A critical step in SMX assembly is the recruitment of MUS81-EME1 to SLX4 in early mit...

Molecular profiling of breast cancer in native American women reveals distinc...

Guo(F),Littlepage(LE),Stack(MS),Li(J) NPJ Precis Oncol 2026-03-17

...ERCC1/CUL4A CNV gains), and mutational-signature analysis indicated greater MMR- and AID/POLE-associated exposures in th...

Tagln1-Cre driven Ercc1 deficiency reveals sex specific effects on adipose ti...

Jüttner(AA),Delhanty(PJD),Raben(JD),Goos(Y... Endocrinology 2026-09-16

...Ercc1 in mice (Tagln1-Cre Ercc1 mice) leads to accelerated aging of VSMC and perivascular adipocytes resulting in vascul...

Rad1-Rad10 uses different interfaces to interact with pathway-specific DNA re...

Rodríguez González(J),Herman(OT),Lewis(KE)... Nucleic Acids Res 2026-09-07

Saccharomyces cerevisiae Rad1-Rad10 (XPF-ERCC1 in humans) is a 3'-flap endonuclease with key roles in DNA repair. Pathwa...

Comprehensive Investigation of a Novel Schiff Base: Synthesis, Anticancer Eff...

Agbektas(T),Pazarcı(Ö),Tas(A),Huseynzada(A... Pharmaceuticals (Basel) 2026-02-18

...ERCC1, ATR, and PRKDC were quantified through qPCR using the ΔΔCt method. Molecular docking and DFT analyses were perfor...

Pan-cancer multi-omics analysis of pharmacogenomic alterations.

AlMulla(A),Kaur(S),Balyan(P),Al-Saafin(S),... Front Bioinform None

...ERCC1, and SLC29A1. Module-level pharmacogenomic alteration was not significantly associated with survival in explorator...

Cyclin D1 regulates the hepatic response to feeding: Evidence for non-cell cy...

Wu(H),Hauser(JI),Yang(N),Timchenko(N),Klae... bioRxiv 2026-05-28

...Ercc1-deficient mice. Cyclin D1 was upregulated in MASLD and diminished with successful treatment. CYD-1 was induced by ...

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