Imran(M) Mol Divers 2026-04-00

...PTPN1 and NFKB1. This integrative computational study combines machine learning, structural modeling, and network pharma...

Wang(AZ),Liu(XM),Zhang(LM),Fu(LL),Li(P),Zh... Mol Divers 2026-07-30

...PTPN1 (PTP1B) as a potential candidate protein, although this predicted interaction requires further experimental valida...

Zhan(Z),Shi(D),Huang(R),Dong(D),Zhou(L),Re... Int Immunopharmacol 2026-09-15

...PTPN1 as an influencing factor for prognosis of HCC patients. Gene function and pathway analyses revealed that PTPN1 is ...

Sil(P),Tiwari(R),Garisetti(V),Baskaran(SP)... Comput Biol Chem 2026-10-00

...PTPN1, GLP1R, and DPP4. SHD-Target-Drug profiling demonstrated convergence with clinically validated drug combinations. ...

Liu(H),Xia(C),Zhang(Y),Gan(Y),Cheng(L),Wan... Int J Biol Sci None

...PTPN1) promoter to transcriptionally regulate PTPN1, thereby driving FMT. In vivo, intratracheal delivery of Ybx1-target...

Tanisha(MH),Siddique(MA),Ahmed(Z),Mustafa(... Health Sci Rep 2026-05-00

...PTPN1, and AKAP1, have also been linked to a mitochondrial interaction network that influences Bax localization and retr...

Hu(L),Guo(L),Zhang(M),Wei(J),Huang(Q),Chen... J Med Chem 2026-05-28

...PTPN1 selectivity >20-fold). Compared to previous PTPN2 degraders, it displays lower molecular weight, fewer hydrogen bo...

Liu(N),Li(Y),Tang(M),Cao(Y),Shang(L),Shi(F... Pharmaceuticals (Basel) 2026-04-09

...PTPN1 via in vitro experiments and nude mouse xenograft models. Results: Resveratrol inhibited EBV-positive cell viabili...

Zhai(Z),Wu(F),Sheng(G),Jia(B),Jia(B),Du(P)... Pharmaceuticals (Basel) 2026-04-21

...PTPN1-binding modes. Mechanistically, organoid proteomics indicated that DHE engagement with PTPN1 disrupts ER membrane ...

Huang(C),Chen(J),Chen(R),Cao(L) Front Chem None

Colorectal cancer remains a major clinical challenge, and dual targeting of PTPN1 and PTPN2 represents a promising strat...