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Sex Differences in Dietary-Induced Liver Steatosis and Insulin Receptor-Relat...

Cespuglio(R),Zabegalov(K),de Munter(JPM),G... Int J Mol Sci 2026-03-20

...Ptpn1, Cyp4a14, Acsl1, and Pten showed differential expression between male and female SERT-KO mice fed WD. Several diff...

Integrating Untargeted Metabolomics and Transcriptomics in Mice with Pulmonar...

Sha(Y),Zhao(X),Zhu(H),Li(Y),Shao(M),Ding(S... Pathogens 2026-02-27

...Ptpn1, Dgat2, and Alox5ap and downregulated Cyld, Zfp61, and Mapk11. Metabolomic profiling revealed 113 differentially a...

PTPN1/PTPN2 inhibition improves NK cancer therapy by enhancing IL-2 and mitig...

Feng(CH),Peltier(L),Chouleur(T),DiPonzio(M... EMBO Rep 2026-05-00

...PTPN1 and PTPN2 (PTPN1/N2) in NK cells significantly enhances anti-tumor cytolytic activity both in vitro and in vivo. T...

Machine learning and free energy clustering reveal PAH protein binding linked...

Chen(C),He(Y),Ni(Y),Song(D),Chu(M),Zhang(W... iScience 2026-04-17

...PTPN1, and ITGA4 as candidate core PAH targets enriched in neuroinflammation, microglial activation, lipid metabolism, a...

Negative correlation between microRNA and insulin sensitivity gene expression...

Podraza(J),Wąsowski(M),Jonas(MI),Lisik(W),... Nutr Metab (Lond) 2026-04-13

...PTPN1, PTPN2) is altered in the adipose tissue of patients with obesity due to miRNA interference, predisposing them dir...

Identifying ICAM-1 as a Therapeutic Target for Cytokine Storm in Human Macrop...

Chen(S),Wu(D),Zheng(Z),Luo(Y),Zhang(L) Molecules 2026-03-27

...PTPN1), E74-like ETS transcription factor 4 (ELF4) and guanylate binding protein 2 (GBP2). Then, the LINCS L1000 charact...

PTPN1 Regulation via YBX1-PTBP1 Interaction Promotes Fibroblast Activation an...

Liu(H),Xia(C),Zhang(Y),Gan(Y),Cheng(L),Wan... Int J Biol Sci None

...PTPN1) promoter to transcriptionally regulate PTPN1, thereby driving FMT. In vivo, intratracheal delivery of Ybx1-target...

Network pharmacology refined with non-ubiquity and decoy-controlled molecular...

Santos-Enriquez(AK),Dayrit(FM),de Jesus(AJ... Front Bioinform None

...PTPN1), 11-beta-hydroxysteroid dehydrogenase 1 (HSD11B1), peroxisome proliferator-activated receptor α (PPARα), peroxiso...

Dietary eriodictyol ameliorates hyperglycemia and multi-organ damage in strep...

Deng(X),Zheng(J),Xiao(C) J Sci Food Agric 2026-08-25

...Ptpn1, Pten, Socs3). In the liver, it shifted metabolism from gluconeogenesis (G6pc, Pck1) toward glycolysis (Gck, Pklr)...

PTPN1 and PTPN2 cooperatively set interferon responsiveness thresholds that g...

Poirier(AJ),Feng(CH),Walback(E),Su(R),Hinc... Proc Natl Acad Sci U S A 2026-08-18

...PTPN1 and PTPN2 as cooperative regulators of tumor immune resistance. Dual genetic ablation of PTPN1/2 in cancer cells e...

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