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Sirtuin 1 mediated ceramide metabolism regulates intestinal mechanical barrie...

Ma(X),Liu(Q),Mai(K),Zhang(Y) Int J Biol Macromol 2026-04-00

...sgpp2) and ceramide catabolism (sgms1a, ugcg, b4galt, and sphk1) in the same tissue. Conversely, compared to the pcDNA3....

Mechanisms of synergistic action between olaparib and KPT-330 in pancreatic c...

Yang(Y),Zhang(Y),Zhang(Y),Su(H),Dong(H),Ji... Cell Biol Toxicol 2026-07-21

...SGPP2, a tumor-associated protein, thereby inhibiting the IL-6/JAK2/STAT3 signaling pathway. SGPP2 is proposed as a key ...

SGPP2 Ameliorates Chronic Heart Failure by Attenuating ERS via the SIRT1/AMPK...

Kang(Y),Wang(Y),Wang(L),Fu(L) Curr Issues Mol Biol 2026-01-19

...SGPP2, and STAT3) were identified through bioinformatics analysis, with SGPP2 showing the most significant differential ...

A Tertiary Lymphoid Structure-Derived Prognostic Signature Integrates Immune ...

Zhou(X),Zhao(Z),Huang(K),Ma(G) Hum Mutat None

...SGPP2) that stratified patients into groups with significantly different overall survival. The TLS score remained an ind...

TFAP2A regulates SGPP2 transcription to promote lipid accumulation and activa...

Li(Q),Li(J),Zhang(C),Deng(Y),Yang(B),Ma(L)... J Transl Med 2026-03-04

...SGPP2 in LUAD cells, whereas SGPP2 reciprocally inhibits TFAP2A expression. Downstream pathway analysis revealed that SG...

DKC1 promotes colorectal cancer progression and therapy resistance by dysregu...

Khan(UK),Goel(A),Nigam(S),Chaudhary(N),Pra... Nat Commun 2026-05-18

...SGPP2, a critical sphingolipid metabolism mediator. Importantly, DKC1-mediated sphingolipid dysregulation promotes first...

Immune cells in dorsal root ganglia are associated with pruritus in a mouse m...

Singto(T),Sergeeva(A),Filor(V),Vidak(J),Kl... J Neuroimmunol 2025-07-15

...Sgpp2). Subsequent functional experiments targeting CTSS in co-culture studies validated suppressed response to pruritog...

Elucidating the genetic basis of earlobe color in Qingyuan partridge chickens...

Liu(X),Wu(R),Hao(T),Ye(H),Zhang(Z),Lei(Z),... Poult Sci 2025-10-00

...SGPP2, and SMPD4 contribute to the formation of white earlobes by regulating the metabolism and deposition of relevant l...

Tumor suppressor microRNA-31 inhibits gastric carcinogenesis by targeting Sma...

Ruoming(W),Zhen(Y),Tengteng(Z),Jisheng(H) Cancer Gene Ther 2016-09-13

...SGPP2 and Smad4 were proven to be the direct target of miR-31. SGPP2 and Smad4 at mRNA and protein levels were negativel...

Potential Link between the Sphingosine-1-Phosphate (S1P) System and Defective...

Barnawi(Jameel),Tran(Hai),Jersmann(Hubertu... PLoS One 2016-06-07

...SGPP2, SGPL1) in bronchoalveolar lavage-derived alveolar macrophages from 10 healthy controls, 7 healthy smokers and 20 ...

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