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Mechanisms of synergistic action between olaparib and KPT-330 in pancreatic c...

Yang(Y),Zhang(Y),Zhang(Y),Su(H),Dong(H),Ji... Cell Biol Toxicol 2026-07-21

...SGPP2, a tumor-associated protein, thereby inhibiting the IL-6/JAK2/STAT3 signaling pathway. SGPP2 is proposed as a key ...

DKC1 promotes colorectal cancer progression and therapy resistance by dysregu...

Khan(UK),Goel(A),Nigam(S),Chaudhary(N),Pra... Nat Commun 2026-05-18

...SGPP2, a critical sphingolipid metabolism mediator. Importantly, DKC1-mediated sphingolipid dysregulation promotes first...

TFAP2A regulates SGPP2 transcription to promote lipid accumulation and activa...

Li(Q),Li(J),Zhang(C),Deng(Y),Yang(B),Ma(L)... J Transl Med 2026-03-04

...SGPP2 in LUAD cells, whereas SGPP2 reciprocally inhibits TFAP2A expression. Downstream pathway analysis revealed that SG...

A Tertiary Lymphoid Structure-Derived Prognostic Signature Integrates Immune ...

Zhou(X),Zhao(Z),Huang(K),Ma(G) Hum Mutat None

...SGPP2) that stratified patients into groups with significantly different overall survival. The TLS score remained an ind...

Sirtuin 1 mediated ceramide metabolism regulates intestinal mechanical barrie...

Ma(X),Liu(Q),Mai(K),Zhang(Y) Int J Biol Macromol 2026-04-00

...sgpp2) and ceramide catabolism (sgms1a, ugcg, b4galt, and sphk1) in the same tissue. Conversely, compared to the pcDNA3....

SGPP2 Ameliorates Chronic Heart Failure by Attenuating ERS via the SIRT1/AMPK...

Kang(Y),Wang(Y),Wang(L),Fu(L) Curr Issues Mol Biol 2026-01-19

...SGPP2, and STAT3) were identified through bioinformatics analysis, with SGPP2 showing the most significant differential ...

Elucidating the genetic basis of earlobe color in Qingyuan partridge chickens...

Liu(X),Wu(R),Hao(T),Ye(H),Zhang(Z),Lei(Z),... Poult Sci 2025-10-00

...SGPP2, and SMPD4 contribute to the formation of white earlobes by regulating the metabolism and deposition of relevant l...

Immune cells in dorsal root ganglia are associated with pruritus in a mouse m...

Singto(T),Sergeeva(A),Filor(V),Vidak(J),Kl... J Neuroimmunol 2025-07-15

...Sgpp2). Subsequent functional experiments targeting CTSS in co-culture studies validated suppressed response to pruritog...

Tumor suppressor microRNA-31 inhibits gastric carcinogenesis by targeting Sma...

Ruoming(W),Zhen(Y),Tengteng(Z),Jisheng(H) Cancer Gene Ther 2016-09-13

...SGPP2 and Smad4 were proven to be the direct target of miR-31. SGPP2 and Smad4 at mRNA and protein levels were negativel...

Potential Link between the Sphingosine-1-Phosphate (S1P) System and Defective...

Barnawi(Jameel),Tran(Hai),Jersmann(Hubertu... PLoS One 2016-06-07

...SGPP2, SGPL1) in bronchoalveolar lavage-derived alveolar macrophages from 10 healthy controls, 7 healthy smokers and 20 ...

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