Pattanayak(SP),Darawshi(O),Hajihassani(O),Wi… Mol Cancer 2026-05-27

...TBC1D7. Small molecules that activate mTOR by blocking the TSC are lacking. We applied in silico docking and medicinal c...

Misal(S),Patil(A),Chhotaray(S),Alex(R),Gandh… Vet Res Commun 2026-08-15

...TBC1D7, and SIRT5. These genes are implicated in transcriptional regulation, intracellular signaling, metabolic processe...

Gu(NH),Luo(LJ),Yang(NP),Yang(YP),Li(GJ),Ou-Y… Reprod Sci 2026-08-00

...TBC1D7, plays an important role in the onset of endometrial-related diseases through the TSC-mTORC1 axis. However, the r...

Pattanayak(SP),Darawshi(O),Hajihassani(O),Wi… Res Sq 2026-04-23

...TBC1D7. Small molecules that activate mTOR by blocking the TSC are lacking. We applied in silico docking and medicinal c...

Dibble(Christian C),Cantley(Lewis C) Trends Cell Biol 2016-06-03

...TBC1D7)] switches on Rheb at the lysosome, where mTORC1 is activated. Integration of PI3K- and amino acid-dependent sign...

Qin(Jiayue),Wang(Zhizhi),Hoogeveen-Westervel… J Biol Chem 2016-10-07

...TBC1D7 complex and biochemical characterization of the TSC1-TBC1D7 interaction. TBC1D7 interacts with the C-terminal reg...

Shimobayashi(Mitsugu),Hall(Michael N) Cell Res 2016-10-12

...TBC1D7), a negative regulator of mTORC1. Amino acids signal to mTORC1 independently of the TSC complex. Here, we review ...

Tsetsos(Fotis),Padmanabhuni(Shanmukha S),Ale… Front Neurosci 2016-08-08

...TBC1D7, GUCY1A3, RAP1GDS1, and CHST11. TBCD17 harbors the top scoring SNP, rs1866863 (p:3.23E-07), located in a regulato...

Alfaiz(Ali Abdullah),Micale(Lucia),Mandriani… Hum Mutat 2015-01-29

...TBC1D7 mutations and defining a TBC1D7 syndrome. Our work reinforces the involvement of TBC1D7 in the regulation of mTOR...

Santiago Lima(Arthur Jorge),Hoogeveen-Wester… PLoS One 2015-01-06

...TBC1D7 mutations have not been reported in TSC patients but homozygous inactivation of TBC1D7 causes megaencephaly and i...