...TBC1D7, plays an important role in the onset of endometrial-related diseases through the TSC-mTORC1 axis. However, the r...
...TBC1D7. Small molecules that activate mTOR by blocking the TSC are lacking. We applied in silico docking and medicinal c...
...TBC1D7. Small molecules that activate mTOR by blocking the TSC are lacking. We applied in silico docking and medicinal c...
...TBC1D7, and SIRT5. These genes are implicated in transcriptional regulation, intracellular signaling, metabolic processe...
...TBC1D7), a negative regulator of mTORC1. Amino acids signal to mTORC1 independently of the TSC complex. Here, we review ...
...TBC1D7)] switches on Rheb at the lysosome, where mTORC1 is activated. Integration of PI3K- and amino acid-dependent sign...
...TBC1D7 complex and biochemical characterization of the TSC1-TBC1D7 interaction. TBC1D7 interacts with the C-terminal reg...
...TBC1D7, GUCY1A3, RAP1GDS1, and CHST11. TBCD17 harbors the top scoring SNP, rs1866863 (p:3.23E-07), located in a regulato...
...TBC1D7 mutations have not been reported in TSC patients but homozygous inactivation of TBC1D7 causes megaencephaly and i...
...TBC1D7 mutations and defining a TBC1D7 syndrome. Our work reinforces the involvement of TBC1D7 in the regulation of mTOR...
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