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Correlations between TSC Expression and Menorrhagia in Adenomyosis Patients.

Gu(NH),Luo(LJ),Yang(NP),Yang(YP),Li(GJ),Ou-Y… Reprod Sci 2026-08-00

...TBC1D7, plays an important role in the onset of endometrial-related diseases through the TSC-mTORC1 axis. However, the r...

AcTor, a novel mTOR stimulator, potentiates ixazomib for the treatment of acute…

Pattanayak(SP),Darawshi(O),Hajihassani(O),Wi… Mol Cancer 2026-05-27

...TBC1D7. Small molecules that activate mTOR by blocking the TSC are lacking. We applied in silico docking and medicinal c...

AcTor, a novel mTOR stimulator, potentiates ixazomib for the treatment of acute…

Pattanayak(SP),Darawshi(O),Hajihassani(O),Wi… Res Sq 2026-04-23

...TBC1D7. Small molecules that activate mTOR by blocking the TSC are lacking. We applied in silico docking and medicinal c...

Candidate genomic regions associated with differential clinical response to lum…

Misal(S),Patil(A),Chhotaray(S),Alex(R),Gandh… Vet Res Commun 2026-08-15

...TBC1D7, and SIRT5. These genes are implicated in transcriptional regulation, intracellular signaling, metabolic processe...

Multiple amino acid sensing inputs to mTORC1.

Shimobayashi(Mitsugu),Hall(Michael N) Cell Res 2016-10-12

...TBC1D7), a negative regulator of mTORC1. Amino acids signal to mTORC1 independently of the TSC complex. Here, we review ...

Regulation of mTORC1 by PI3K signaling.

Dibble(Christian C),Cantley(Lewis C) Trends Cell Biol 2016-06-03

...TBC1D7)] switches on Rheb at the lysosome, where mTORC1 is activated. Integration of PI3K- and amino acid-dependent sign...

Structural Basis of the Interaction between Tuberous Sclerosis Complex 1 (TSC1)…

Qin(Jiayue),Wang(Zhizhi),Hoogeveen-Westervel… J Biol Chem 2016-10-07

...TBC1D7 complex and biochemical characterization of the TSC1-TBC1D7 interaction. TBC1D7 interacts with the C-terminal reg...

Meta-Analysis of Tourette Syndrome and Attention Deficit Hyperactivity Disorder…

Tsetsos(Fotis),Padmanabhuni(Shanmukha S),Ale… Front Neurosci 2016-08-08

...TBC1D7, GUCY1A3, RAP1GDS1, and CHST11. TBCD17 harbors the top scoring SNP, rs1866863 (p:3.23E-07), located in a regulato...

Identification of regions critical for the integrity of the TSC1-TSC2-TBC1D7 co…

Santiago Lima(Arthur Jorge),Hoogeveen-Wester… PLoS One 2015-01-06

...TBC1D7 mutations have not been reported in TSC patients but homozygous inactivation of TBC1D7 causes megaencephaly and i...

TBC1D7 mutations are associated with intellectual disability, macrocrania, pate…

Alfaiz(Ali Abdullah),Micale(Lucia),Mandriani… Hum Mutat 2015-01-29

...TBC1D7 mutations and defining a TBC1D7 syndrome. Our work reinforces the involvement of TBC1D7 in the regulation of mTOR...

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