Literature Search

Li(S),Zhang(N),Yin(Y) Front Oncol None

...TSC2 frameshift mutation. The patient underwent open right partial nephrectomy. Histopathology demonstrated a malignant ...

Farach(LS),Leu(C),Lal(D),Smith(AR),Montanucc… Genet Med 2026-06-00

...TSC2 may be warranted, especially as the diagnosis of TSC could mask these second neurodevelopmental disorders and knowl...

Sugimoto(H),Sawa(N),Oba(Y),Mizuno(H),Sekine(… CEN Case Rep 2026-04-18

...TSC2 mutation, which is linked to tuberous sclerosis, and HNF1B mutation, which is linked to diabetes. To our knowledge,...

Yang(L),Huang(L),Ren(S) Biochim Biophys Acta Mol Cell… 2026-04-00

...TSC2)-deficient cells. The IL-6 levels in the lung tissue and serum of the patients were detected using immunohistochemi...

Xu(J),Cheng(L),Ma(S),Gan(C),Chai(J),Zheng(X)… Int J Biol Sci None

...TSC2) expression, suppressing mTOR activity and altering autophagic processes in tumor cells. This regulation was mediat...

Han(MH),Chu(J),Wang(Y),Guo(ZH),Liu(Y),Yu(WJ)… Zhonghua Bing Li Xue Za Zhi 2026-04-08

...TSC2 and mTOR mutations in 1 case, a TSC2 mutation in 1 case, and germline TSC1 mutations in 2 cases. Follow-up of the c...

Del Baldo(G),Milano(GM),Salvatore(MD),Mastro… Oncologist 2026-06-06

...TSC2 genes, resulting in constitutive mTOR signaling pathway activation, a central driver of tumorigenesis and a key the...

Yeung(MCF),Cheung(HMH),Liu(APY),Shek(TWH) Mod Pathol 2026-06-00

...TSC2 deletions and NTRK1 and ERBB3 amplifications found in a subset of cases. No pathogenic fusions were detected. Trans...

Lei(X),Lang(T),Li(P),Wu(C) Int J Mol Sci 2026-03-27

...Tsc2+/- MEFs. Mechanistically, Tsc1 or Tsc2 deletion reduced global H3K27me3, correlating with increased viability, acce...

Tan(Z),Tian(A),Ma(R),Yang(C),Liu(X),Wang(L),… J Agric Food Chem 2026-03-18

...TSC2)/mechanistic target of rapamycin complex 1 (mTORC1) axis to improve insulin resistance, in which the effects were c...