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RNA-seq of depdc5-/-, tsc2-/-, depdc5-/- x tsc2-/- and wildtype zebrafish larvae

Samples:16 Organism:Danio rerio, Danio rerio Type:RNA-seq of coding RNA Sept. 12, 2022

...tsc2-/-, depdc5-/- x tsc2-/- and wildtype zebrafish larvae to provide insights into the neuropathological processes unde...

Lineage recording in human cerebral organoids (iTracer-perturb)

Samples:3 Organism:Homo sapiens, Homo sapiens Type:RNA-seq of coding RNA from single cells… Nov. 3, 2021

...TSC2 perturbation and lineage recording.

Uncoupling effects of ERalfa on LKB1/AMPK interaction upon adiponectin exposure…

Samples:18 Organism:Homo sapiens, Homo sapiens Type:RNA-seq of coding RNA Feb. 27, 2020

...TSC2/mTOR/p70S6k. In MCF-7 cells upon adiponectin AMPK signaling was not working, keeping its downstream protein Acetyl...

Modeling the Neuropathology of Tuberous Sclerosis with Human Stem Cells Reveals…

Samples:24 Organism:Homo sapiens Type:RNA-seq of coding RNA July 25, 2016

...TSC2 deficient neural stem cells showed severely reduced neuronal functional maturation and characteristics of astroglio...

Modeling the Neuropathology of Tuberous Sclerosis with Human Stem Cells Reveals…

Samples:48 Organism:Homo sapiens Type:RNA-seq of coding RNA July 25, 2016

...TSC2 deficient neural stem cells showed severely reduced neuronal functional maturation and characteristics of astroglio...

Regulation of PERK-eIF2α Signaling by Tuberous Sclerosis Complex-1 Controls Hom…

Samples:2 Organism:Mus musculus Type:RNA-seq of coding RNA July 22, 2016

...TSC2, exhibits white matter abnormalities including CNS myelin deficits. however, underlying mechanisms are not fully u...

Transcription profiling by high throughput sequencing of uterine-specific Tsc2-…

Samples:18 Organism:Mus musculus Type:RNA-seq of coding RNA Feb. 26, 2016

...Tsc2-null LAM like cells, we performed RNAseq on uteri from 12-week old wild-type (WT) and uterine-specific Tsc2-null (K...

Peripheral blood mononuclear cells gene expression reflects adaptive response a…

Samples:36 Organism:Rattus norvegicus Type:transcription profiling by array Dec. 7, 2015

...Tsc2). HP diet also impaired the expression of genes related to glucose metabolism and insulinemia (Glut-4/Slc2a4, Sfxn5...

Expression data from MCF7 cells: control or tuberin-depleted

Samples:4 Organism:Homo sapiens Type:transcription profiling by array April 28, 2015

...TSC2-targeted shRNA (leading to tuberin depletion). MCF7 cells were cultured in standard conditions, transduced, selecte...

Evidence that TSC2 acts as a transcription factor and binds to and represses th…

Samples:8 Organism:Homo sapiens Type:transcription profiling by array Nov. 5, 2013

...TSC2, gene expression profiling of two clones stably overexpressing TSC2 was performed. The gene expression profiles of ...

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