...Apc2. We have obtained three-dimensional (3D) models of human and Xenopus APC/C by angular reconstitution and random con...
...APC2. Two resemble the truncation alleles found in human tumors and one is a protein null. We generated ovaries and embr...
...Apc2 (Cullin), Apc11 (RING), and Doc1/Apc10, and another that contains the three TPR subunits (Cdc27, Cdc16, and Cdc23)....
...Apc2, Apc10, Csn2) as well as genes the function of which had not been previously ascribed to cell cycle regulation (Cdc...
...APC2, APC11, CDC16, CDC23, CDC27, and DOC1) were identified in the Trypanosoma brucei genome data base. Expression of si...
...Apc2 during mouse development. In the adult brain, Apc2 is expressed predominantly in neurons and throughout the brain. ...
...Apc2 modification resulted in compounds having differently modified activities (high antidiuretic potency, low and grade...
...Apc2 in mice. Deletion of Apc2 in quiescent hepatocytes caused re-entry into the cell cycle and arrest in metaphase, res...
...apc2 ts mutant. By yeast two-hybrid assays, we demonstrate an interaction of APC2 with two other APC/C subunits: APC11 a...
...APC2 and APC11 with E2 enzymes is sufficient for ubiquitination reactions, but the functions of most other subunits are ...
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