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Conversational AI-Enabled Precision Oncology Reveals Context-Dependent MAPK P...

Diaz(FC),Waldrup(B),Carranza(FG),Manjarrez... Cancers (Basel) 2026-01-17

...PDGFRB alterations were more frequent in FOLFOX-treated EO H/L tumors relative to EO NHW counterparts. In late-onset H/L...

Targeted Therapy for a Rare PDGFRB-Rearranged Myeloproliferative Neoplasm: A ...

Barbato(C),Lasorsa(VA),Grimaldi(F),Errichi... Int J Mol Sci 2026-01-08

...PDGFRB gene. WGS and RNAseq identified a fusion between PDGFRB and CCDC88C, causing the constitutive activation of PDGFR...

A case report and a literature review of Myeloid/Lymphoid Neoplasm with Eosin...

Čemažar(L),Šlajpah(K),Gredelj Šimec(N),Pod... Ann Hematol 2026-01-14

...PDGFRB, FGFR1, JAK2, FLT3, ETV::ABL1 and other partner genes/variants. Among these, gene rearrangements involving PCM1::...

Therapeutic effects of the n-butanol extract of Potentilla freyniana Bornm. i...

Wang(Y),Zhang(Z),Cao(L),Huang(S),Huang(X),... J Ethnopharmacol 2026-01-10

...PDGFRB, AKT1, FGFR1, MAPK1, and EZH2 - the n-butanol extract of PFB robustly disrupts cancer cell cycle progression and ...

Based on network pharmacology and experiments to investigate the inhibitory e...

Yang(X),Xiao(JH),Li(X),Liu(RM),Yuan(Q) J Ethnopharmacol 2026-02-28

...PDGFRB, TLR4). In addition, Licoricesaponin G2 substantially downregulated the protein expression of cancer stem cell ma...

Endothelial PDGF Signaling Dysregulation Impairs Testicular Interstitial Home...

Zhang(W),Hong(K),Tang(Y),Cui(L),Lu(X),Chen... Adv Sci (Weinh) 2026-04-00

...PDGFRB, collectively weakening intercellular connectivity. This disruption silences the JUND-MCL1 survival program in Le...

The protein-protein interaction network analysis in idiopathic posterior uvei...

Shariati(MM),Moravvej(Z) Indian J Ophthalmol 2026-02-01

...PDGFRB, ORM1, IL23A, and TIMP1. Proteins such as IL6, KITLG, and STAT4 emerged as critical bottlenecks based on betweenn...

Decoding Diabetes: Hub Genes as Pivotal Players in Cardiomyopathy and Kidney ...

Liu(J),Chen(W),Zou(Y),Xu(J) Endocr Metab Immune Disord ... 2026-01-15

...PDGFRB, and SULF1), which were validated as dysregulated in in vitro and in vivo models. Computational screening reveale...

Novel insights into meningioma brain invasion with spatial transcriptomic pro...

Maier(AD),Laurentiussen(CO),Michaelsen(SR)... Acta Neuropathol Commun 2026-01-04

...PDGFRB compared to non-invasive meningiomas (n = 8). Meningioma cell-enriched populations from the brain-meningioma bord...

Tcf21 modulates fibroblast activation and promotes cardiac fibrosis after inj...

Baba(Y),Maezawa(Y),Kondo(N),Minamizuka(T),... Sci Rep 2025-08-02

...Pdgfrb-Erk pathway was severely suppressed in Tcf21-knockout fibroblasts. Chromatin immunoprecipitation-sequencing assay...

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