Mani(Ram-Shankar) Drug Discov Today 2015-04-08

Speckle-type POZ (pox virus and zinc finger protein) protein (SPOP) is an E3 ubiquitin ligase adaptor protein that is fr...

Khani(Francesca),Mosquera(Juan Miguel),Park(… Clin Cancer Res 2015-07-31

The aim of this study was to compare the frequency of ERG rearrangement, PTEN deletion, SPINK1 overexpression, and SPOP ...

Zhang(Pingzhao),Gao(Kun),Tang(Yan),Jin(Xiaof… Hum Mutat 2015-05-11

...SPOP is potentially a key driver for prostate cancer development and progression. However, how SPOP mutations contribute...

Zeng(Chunyan),Wang(Yao),Lu(Quqin),Chen(Jiang… J Exp Clin Cancer Res 2015-09-22

...SPOP and Gli2 was visualized by immunofluorescent staining in gastric cancer cells.,Immunohistochemical staining of SPOP...

García-Flores(María),Casanova-Salas(Irene),R… Eur J Cancer 2015-01-20

...SPOP expression levels being associated to the worst prognosis. Multivariate analysis demonstrated that low levels of SP...

Gao(Dong),Vela(Ian),Sboner(Andrea),Iaquinta(… Cell 2015-05-11

...SPOP mutation, SPINK1 overexpression, and CHD1 loss. Whole-exome sequencing shows a low mutational burden, consistent wi...

Buckles(Eric),Qian(Chiping),Tadros(Andrew),M… Asian J Androl 2015-08-13

...SPOP expression in tumors carrying SPOP mutations than their matched normal prostate tissues. In addition, SPOP mutation...

Jones(Siân),Stransky(Nicolas),McCord(Christi… Nat Commun 2015-12-17

...SPOP and in chromatin assembly factor BAZ1A, in nearly two thirds of cases. Alterations in genes with potential clinical...

Geng(Chuandong),Rajapakshe(Kimal),Shah(Shrij… Cancer Res 2015-03-04

...SPOP substrates may make to the pathophysiology of SPOP-mutant (mt) prostate adenocarcinomas are unknown. Using an unbia...

Lai(John),Batra(Jyotsna) Asian J Androl 2015-05-21

...SPOP gene that were identified in the aforementioned exome sequencing studies, particularly in the context of SPOP-media...