Yan(P),Xue(X),Hou(T),Wang(J),Jiang(W),Wang... Biochim Biophys Acta Rev Ca... 2026-04-00

...SPOP's tumor suppressor functions and structural features, upstream regulatory mechanisms, and SPOP-targeting therapeuti...

Bakhoum(SF),Laughney(AM) Cancer Cell 2026-02-09

...SPOP-USP7-TREX1 axis that controls cytosolic DNA clearance after DNA damage, thereby gating tumor-cell-intrinsic cyclic ...

Park(JJ),Howard(LE),Fragkogianni(S),George... Clin Genitourin Cancer 2026-03-00

...SPOP-mutated (SPOPmut) patients matched to 223 SPOP wild-type (SPOPwt) patients who received first-line ARPI therapy in ...

Oveisi(AR),Daliran(S),Blanco(M),Dhakshinam... Chem Soc Rev 2026-03-09

...SPOPs), where robust frameworks are combined with the strong Brønsted acidity of -SO3H groups. We describe the design an...

Valle(LF),Scobie(M),Rowe(K),Pritchard(CC),... Oncologist 2026-07-08

...SPOP) and rates of actionable and non-actionable alterations were compared between these groups. cfDNA alterations were ...

Malpani(A),Ryan(JT),Yu(H),Soodana-Prakash(... BJU Int 2026-05-00

...SPOP and CHD1 mutations. Limitations include small sample size and single-institution setting. The PAM50 basal-luminal s...

Xiong(X),Zhu(W),Huang(W),Zhang(S),Deng(Q),... MedComm (2020) 2026-08-00

...SPOP, and CHD1 are significantly less frequent. Notably, the prevailing focus on hereditary EOPC has inadvertently led t...

Olivares-Huerta(O),Castro-Coyotl(DM),Crisa... Cureus 2026-04-00

Nabais Sá-de Vries syndrome (NSDVS) is a rare disease caused by a heterozygous mutation in the SPOP gene (17q21), which ...

Brenna(D),Puglisi(M),Epistolio(S),Barizzi(... Int J Mol Sci 2026-09-01

...SPOP, PIK3CA, and AR amplification. IT-HPV seems to be infrequent in metastatic and locally advanced PCa in Western popu...

Glennie(L),Huang(DT) Mol Cell 2026-08-06

...SPOP that can become dysregulated in cancer. SPOP oligomers form inactive double donuts or active linear filaments, as s...