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Age exaggerates proinflammatory cytokine signaling and truncates signal trans...

Dinapoli(V A),Benkovic(S A),Li(X),Kelly(K ... Neuroscience 2011-01-20

...SOCS3), which is associated with termination of astrogliosis, was enhanced as a function of age after MCAO. These findin...

Involvement of the JAK-STAT pathway and SOCS3 in the regulation of adiponecti...

Akifusa(Sumio),Kamio(Noriaki),Shimazaki(Yo... J Cell Biochem 2011-01-31

...SOCS3 mRNA expression and protein production. We examined SOCS3-overexpressing RAW 264 cells to investigate the role of ...

T cell treatment with small interfering RNA for suppressor of cytokine signal...

Moriwaki(Atsushi),Inoue(Hiromasa),Nakano(T... Am J Respir Cell Mol Biol 2011-06-07

...SOCS3 of T cells by crossing SOCS3-floxed (SOCS3(flox/flox)) mice with CD4-Cre transgenic mice. CD4-Cre × SOCS3(flox/flo...

[Construction of SOCS3 recombinant adenovirus and its expression in porcine p...

Yang(Shuangjuan),Xu(Chengquan),Wu(Jiangwei... Sheng Wu Gong Cheng Xue Bao 2011-09-22

...SOCS3) and obtain infectious adenoviral particles, SOCS3 gene was amplified from plasmid pcDNA3-SOCS3 and subcloned into...

Autocrine effects of interleukin-6 mediate acute-phase proinflammatory and ti...

Wood(Michael W),Breitschwerdt(Edward B),Go... Infect Immun 2011-03-15

...SOCS3 expression. Using exogenous IL-6, a microarray approach, and quantitative reverse transcriptase PCR (q-RT-PCR), 5 ...

Negative impact of rAAV2 mediated expression of SOCS3 on the regeneration of ...

Hellström(M),Muhling(J),Ehlert(E M),Verhaa... Mol Cell Neurosci 2011-05-09

...SOCS3 expression on the survival and regeneration of injured adult RGCs by injecting a bicistronic rAAV2-SOCS3-GFP vecto...

1,25-dihydroxyvitamin D3 modulates cytokine production induced by Candida alb...

Khoo(Ai-Leng),Chai(Louis Y A),Koenen(Hans ... J Infect Dis 2011-01-11

...SOCS3 mRNA. 1,25(OH)(2)D(3) inhibited TLR2, TLR4, Dectin-1, and MR mRNA and protein expression. In our seasonality study...

ENU mutagenesis identifies mice with morbid obesity and severe hyperinsulinem...

Hong(Chen-Jee),Tsai(Pei-Jane),Cheng(Chih-Y... PLoS One 2011-07-05

...SOCS3 were attenuated in Leptin(145E/145E) mice. Administration of exogenous wild-type leptin attenuated hyperphagia and...

Coexpression of an intronic microRNA and its host gene reveals a potential ro...

Ma(Ning),Wang(Xidi),Qiao(Yu),Li(Fuyuan),Hu... Mol Cell Endocrinol 2011-08-15

...Socs3) and Igf2 mRNAs, respectively. Finally, Socs3, a key putative leptin-resistant factor in obesity, is identified as...

SOCS3 suppresses the expression of IL-4 cytokine by inhibiting the phosphoryl...

Kim(Donghyun),Kim(Seon-Hee),Cho(Sang-Heon)... Mol Immunol 2011-02-18

...SOCS3 constitutively at a high level or at a lower level using shRNA. In RBL-2H3 cells stably expressing SOCS3, the RNA ...

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