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Integrating network pharmacology and transcriptomics reveals the mechanism by...

Wang(S),Feng(YS),Zhang(YK),Wang(SX) J Ethnopharmacol 2027-01-10

...Socs3, IL-6), from which we proposed the "triple imbalance - triple repair" model. Finally, in vitro and in vivo experim...

Leuprolide Acetate Promotes Sensory Recovery and Modulates Dorsal Root Gangli...

Hernández-Jasso(I),Calderón-Vallejo(D),Ávi... Brain Sci 2026-03-20

...Socs3, Fos, Jun, Atf4, and Limk1 were quantified by qPCR. Results: Our results showed that LA treatment exerted a distin...

Integrated miRNAs, Transcriptome, and Metabolome Uncover Underlying Mechanism...

Zhang(L),Liu(X),Li(L),Huang(L),Zhu(Z),Miao... Animals (Basel) 2026-03-16

...SOCS3-a well-established negative regulator of glucose uptake in mammalian skeletal muscle-was significantly upregulated...

Circulating EV miRNA Cargo in Glioblastoma Patients Is Associated with Distin...

Popovic-Vukovic(M),Kolic(I),Stankovic(A),Z... Biomedicines 2026-03-18

...SOCS3, and PTEN, while CCND1 was downregulated. Correlation analyses suggested that certain EV miRNA changes parallel wi...

Systems-Level Analysis of HPAI H5N1 Infection in Ducks: Integrating Transcrip...

Vijayakumar(P),Mishra(A),Rajamanickam(K),R... Int J Mol Sci 2026-03-23

...SOCS3, ACTB, TLR4, TLR7, IL-6, CASP1, and CASP8, which form a central hub in duck antiviral immunity. Some of these gene...

Identification and Analysis of Remimazolam's Potential Therapeutic Mechanisms...

Zhou(J),Hu(W),Luo(Y),Zhang(X),Hu(B),Zou(X) J Inflamm Res None

...SOCS3-were identified. Pathways related to inflammatory response, IL6/JAK/STAT3 signaling, and TNFα/NF-κB signaling were...

TonEBP as a key regulator of hypothalamic leptin signaling and resistance.

Kim(HR),Kang(D),Kim(DH),Jeong(B),Kim(K),Pa... Cell Mol Life Sci 2026-03-31

...SOCS3). TonEBP (+/-) mice exhibited heightened leptin-induced anorexia, increased energy expenditure, and elevated STAT3...

Human milk bacteria assembled into functionally distinct synthetic communitie...

Le Bras(C),Randuineau(G),Cahu(A),Dahirel(P... mSystems 2026-04-21

...SOCS3), and Treg (FOXP3) pathways in ileal and colonic tissues compared with the CTRL group. Systemic immune functions w...

Exosome-derived ncRNAs and proteins: inflammation regulatory mechanisms and b...

Wang(Y),Zhang(J),Liu(J),Li(Y),Zhao(X),Yang(Z) Front Mol Biosci None

...SOCS3/STAT3, repairing the blood-spinal cord barrier. Targeted interventions (engineered/MSC-derived exosomes) restore t...

Elevating Jak-STAT signaling via SOCS3 deletion sustains photoreceptor viabil...

Wang(Y),Nusinowitz(S),Yang(XJ) Cell Commun Signal 2026-04-16

...SOCS3), which acts as a feedback inhibitor to dampen cytokine signaling. In this study, we investigated whether eliminat...

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