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TP53 BRCA1 CRISPR single-cell cancer

Suessmuth(Yvonne),Elliott(Joanne),Percy(Me... Br J Haematol 2010-03-30

...SOCS3 (F136L). Interestingly, the SOCS3(F136L) mutation was detected in a Japanese myeloproliferative disorder patient c...

Tups(A) J Neuroendocrinol 2010-01-21

...SOCS3) and the protein tyrosine phosphatase 1B (PTP1B). The janus kinase 2 (JAK2)-STAT3 signalling pathway might be modu...

Liu(Li),Gu(Hailun),Yang(Jun),Ma(Shuang),Yu... Mol Biol Rep 2010-09-30

...SOCS3 regulation. In this study, a lentiviral vector expressing a shRNA targeting SOCS3 gene (Lv-shSOCS3) is developed a...

Ko(Hwi Jin),Zhang(Zhiyou),Jung(Dae Young),... Diabetes 2010-01-06

...SOCS3 and via SOCS3-mediated inhibition of insulin receptor substrate (IRS)-1 and possibly AMPK in heart. Diet-induced i...

Fuentes(T),Ara(I),Guadalupe-Grau(A),Larsen... Exp Physiol 2010-08-04

...SOCS3) and protein tyrosine phosphatase 1B (PTP1B) in skeletal muscle, which blunt janus kinase 2-dependent leptin signa...

Zhou(Xiaoxu),Li(Dan),Yan(Wei),Li(Weimin) Int J Mol Sci 2010-06-17

...SOCS3) expressions in lesions. Our results suggested that pravastatin's aortic atherosclerosis preventing action via att...

Zhang(Zhuohan),Liu(Qiaofei),Che(Yongzhe),Y... Cancer Res 2010-01-26

...SOCS3 with M2-PK reduced ATP production and impaired DC-based immunotherapy against tumors. Thus, SOCS3, which has been ...

Newbern(Jason M),Shoemaker(Sarah E),Snider... Neuron 2010-01-05

...SOCS3 acts as a key negative regulator of adult optic nerve regeneration.

Smith(Patrice D),Sun(Fang),Park(Kevin Kyun... Neuron 2010-01-05

...SOCS3-gp130 double-knockout mice, suggesting that SOCS3 deletion promotes axon regeneration via a gp130-dependent pathwa...

Koeberlein(Bernd),zur Hausen(Axel),Bektas(... Virus Res 2010-04-26

...SOCS3 protein. In spite of the over expression of its negative regulator SOCS3 we observed a constitutive activation of ...

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