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TPR subunits of the anaphase-promoting complex mediate binding to the activat...

Vodermaier(Hartmut C),Gieffers(Christian),... Curr Biol 2004-01-23

...APC2 and APC11 with E2 enzymes is sufficient for ubiquitination reactions, but the functions of most other subunits are ...

Loss of the anaphase-promoting complex in quiescent cells causes unscheduled ...

Wirth(Karin G),Ricci(Romeo),Giménez-Abián(... Genes Dev 2004-02-12

...Apc2 in mice. Deletion of Apc2 in quiescent hepatocytes caused re-entry into the cell cycle and arrest in metaphase, res...

Expression analyses and interaction with the anaphase promoting complex prote...

Morgan(David),Eley(Lorraine),Sayer(John),S... Hum Mol Genet 2003-07-11

...Apc2. As expected of an Apc2 target, inversin possesses D-boxes and site-directed mutagenesis of the well-conserved D-bo...

Drosophila Apc1 and Apc2 regulate Wingless transduction throughout developmen...

Ahmed(Yashi),Nouri(Ali),Wieschaus(Eric) Development 2002-05-24

...Apc2) appear to have predominantly different tissue distributions, different subcellular localizations and mutually excl...

The anaphase promoting complex/cyclosome is required during development for m...

Kashevsky(Helena),Wallace(Julie A),Reed(Br... Proc Natl Acad Sci U S A 2002-09-27

...APC2 subunit of the anaphase promoting complex/cyclosome. This finding demonstrates that anaphase promoting complex/cycl...

Drosophila APC2 and APC1 have overlapping roles in the larval brain despite t...

Akong(Kathryn),McCartney(Brooke M),Peifer(... Dev Biol 2002-11-05

...APC2 and APC1 in nerves formed by axons of the progeny of each neuroblast-ganglion mother cell cluster. APC2 and APC1 lo...

Drosophila APC2 and APC1 play overlapping roles in wingless signaling in the ...

Akong(Kathryn),Grevengoed(Elizabeth E),Pri... Dev Biol 2002-11-05

...APC2 play overlapping roles in regulating Wingless signaling in the embryonic epidermis and the imaginal discs. Surprisi...

Laser capture microdissection and microarray expression analysis of lung aden...

Miura(Koh),Bowman(Elise D),Simon(Richard),... Cancer Res 2002-07-16

...APC2, contribute to the molecular pathogenesis and tumor progression of tobacco smoke-induced adenocarcinoma of the lung...

APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin lig...

Tang(Z),Li(B),Bharadwaj(R),Zhu(H),Ozkan(E)... Mol Biol Cell 2002-05-29

...APC2 and APC11 is sufficient to catalyze the ubiquitination of human securin and cyclin B1. However, the minimal APC2/11...

Drosophila APC2 and Armadillo participate in tethering mitotic spindles to co...

McCartney(B M),McEwen(D G),Grevengoed(E),M... Nat Cell Biol 2001-12-04

...APC2 all localize to sites of cortical spindle attachment. APC2-Armadillo complexes often localize with interphase micro...

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