Bentires-Alj(Mohamed),Neel(Benjamin G) Cancer Res 2007-04-19

...PTPN1) is an important regulator of mammalian metabolism and also helps control signaling by growth factors, cytokines, ...

Wanic(K),Malecki(M T),Klupa(T),Warram(J H)... Diabet Med 2007-09-27

Recently, an association of Type 2 diabetes (T2DM) with polymorphisms in PTPN1 located on chromosome 20q was reported. W...

Meshkani(Reza),Taghikhani(Mohammad),Mosapo... Arch Med Res 2007-09-27

Protein tyrosine phosphatase 1B (PTP1B), encoded by the PTPN1 gene, efficiently dephosphorylates the insulin receptor, a...

Julien(Sofi G),Dubé(Nadia),Read(Michelle),... Nat Genet 2007-06-20

...Ptpn1-deficient mice or by treatment with a specific PTP1B inhibitor results in significant mammary tumor latency and re...

Fernández-Veledo(S),Nieto-Vazquez(I),Rondi... Diabetologia 2007-09-18

...PTPN1 production and phosphatase activity produced by TNFalpha. In this regard, Ptpn1-deficient brown adipocytes showed ...

Traurig(M),Hanson(R L),Kobes(S),Bogardus(C... Diabetologia 2007-10-23

...PTPN1, while block 2 contains 19 SNPs that cover the entire PTPN1 gene. None of the SNPs, analysed individually or as ha...

Chen(Yan),Shortreed(Michael R),Olivier(Mic... Anal Chem 2007-03-20

...PTPN1 gene and 10 mutations in the cystic fibrosis transmembrane conductance regulator gene. This ability to analyze man...

Cheyssac(Claire),Lecoeur(Cécile),Dechaume(... BMC Med Genet 2006-08-04

...PTPN1 gene located on chromosome 20q13 showing linkage with type 2 diabetes (T2D) in several populations. PTPN1 gene var...

Rao(Gita Subba),Ramachandran(Manoj V),Baja... J Biomol Struct Dyn 2006-03-02

...PTPN1 gene, which encodes PTP1B, is a major risk contributor to type 2 diabetes mellitus (T2DM). Thus, there is compelli...

Bence(Kendra K),Delibegovic(Mirela),Xue(Bi... Nat Med 2006-09-21

...Ptpn1(-/-)) mice. Neuronal Ptpn1(-/-) mice have reduced weight and adiposity, and increased activity and energy expendit...