Zhang(Dan),Wang(Haibo),Sun(Mianen),Yang(Jun)… Carcinogenesis 2015-02-18

...SPOP have been observed in various tumor types with chromosomal aberrations, indicating a role of SPOP in maintaining ge...

Ding(Dacheng),Song(Tao),Jun(Wu),Tan(Zeming),… Int J Oncol 2015-08-11

...SPOP expression was significantly worse than that of SPOP-high patients (P=0.001). In vitro overexpression of SPOP marke...

Rodrigues(Daniel Nava),Butler(Lisa M),Estell… J Pathol 2014-02-07

...SPOP mutant as well as SPINK1-over-expressing subtypes. As the number of targeted therapy agents increases, it is crucia...

Schwend(Tyler),Jin(Zhigang),Jiang(Kai),Mitch… J Biol Chem 2014-01-20

...Spop, and increased the level of Ci. Thus, Dzip1-dependent stabilization of Spop/HIB is evolutionarily conserved and ess...

van Geersdaele(Laura K),Stead(Mark A),Harris… Acta Crystallogr D Biol Cryst… 2014-03-11

...SPOP enhances the ubiquitination of substrates. Here, a dimerization interface in the SPOP C-terminus is identified and ...

An(Jian),Wang(Chenji),Deng(Yibin),Yu(Long),H… Cell Rep 2014-11-07

...SPOP E3 ubiquitin ligase gene is frequently mutated in human prostate cancers. Here, we demonstrate that SPOP recognizes...

Zuhlke(Kimberly A),Johnson(Anna M),Tomlins(S… Prostate 2014-07-01

...SPOP.,We identified a novel SPOP missense mutation (N296I) in a man with prostate cancer diagnosed at age 43. This mutat...

Blattner(Mirjam),Lee(Daniel J),O'Reilly(Cath… Neoplasia 2014-09-09

...SPOP mutations was 8.1% (4.6% to 14.4%), SPOP mutation was inversely associated with ERG rearrangement (P<.01), and SPOP...

Lin(Chuwen),Chen(Miao-Hsueh),Yao(Erica),Song… Dev Biol 2014-09-19

...Spop-mediated degradation of Gli2/3 by Sufu. Thus, controlling protein levels of all three Gli genes by Sufu is a conser...

Jia(Deshui),Dong(Rui),Jing(Ying),Xu(Dan),Wan… Hepatology 2014-12-30

...SPOP, OR5I1, and CDC20B) influence HB cell growth. Moreover, we found that SPOP S119N is a loss-of-function mutation in ...