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Luteolin as a novel therapeutic for diabetic kidney disease: Targeting the ADAM…

Deng(L),Wang(Y),Shi(C),Wu(J),Yao(J),Shen(W),… J Adv Res 2026-04-24

...SYK, and PHrodo+ cell counts. Apoptotic cells in kidney tissue decreased, while Rab5a and Rab7a expression were upregula...

Coptis chinensis Franch. Suppresses Invasive Pulmonary Aspergillosis by Augment…

Jiang(Z),Zhou(L),Wang(J),Sun(H),Cai(L),Yin(H… Curr Issues Mol Biol 2026-04-20

...Syk, Rac2, Ncf1, and Cybb as key nodes associated with the NADPH oxidase complex. Western blot and inhibitor experiments...

Targeting NAV2-mediated Wnt/β-catenin signaling in rheumatoid arthritis: curren…

Padmanaban(D),Krishnan(M) Mol Biol Rep 2026-04-28

...SYK-BTK, Notch, NF-κB, and Wnt/β-catenin, play a significant role in disease progression. Among the emerging molecular p...

Integrative Proteomic and Phosphoproteomic Analysis Reveals Altered Vesicle Tra…

Zhou(L),Li(Y),Wu(M),Tang(D),Zhang(W),Dai(Y) Clin Proteomics 2026-04-28

...SYK, PDGFRA, LCK, PKCA, PKCD, TBK1, AKT1, and DLK were implicated in the underlying pathogenic mechanism, whereas TAK1, ...

Innate lymphoid cells integrate sensing and plasticity to control fungal infect…

Tsymala(I),Penninger(P),Nogueira(F),Jenull(S… Cell Rep 2026-04-20

...Syk/p38-dependent signaling as one of the key drivers of ILC activation following fungal challenges. Aspergillus fumigat...

Potassium suppresses allosteric activation of ZAP-70-dependent T cell receptor …

Roy(S),SenGupta(S),Gangopadhyay(K),Majumder(… J Biol Chem 2026-06-00

...Syk, which is expressed in B cells, is insensitive to potassium concentration. At elevated K+ concentration, the interac...

MIZ-1 controls transcriptional programs required for BCR signaling, actin dynam…

Ross(J),Piskor(EM),Joly-Beauparlant(C),Tabar… Front Immunol None

...SYK, RAF1, AKT and ERK. We demonstrate that these perturbations are associated with altered calcium flux and mitochondri...

Neutrophil Extracellular Traps in Viral Infections: Regulation, Immune Conseque…

Asaba(CN),Gwanyama(BN),Ayuk(HS),Odo(TI),Bita… Cells 2026-03-25

...SYK, MAPKs, and NF-κB. Using SARS-CoV-2 and hepatitis B virus as representative models, we examine how different viral c...

Peripheral blood transcriptomic analysis of patients with rheumatoid arthritis …

Flouda(S),Grigoriou(M),Sentis(G),Grivas(A),M… Arthritis Res Ther 2026-05-06

...Syk and FAK inhibitors are candidate compounds that potentially reverse the transcriptomic signature of RA-ILD progressi...

Troxerutin suppresses the stemness of hepatocellular carcinoma via the Syk/FOXO…

Liu(S),Lin(Y),Xia(H),Li(H),Dou(Y),Luo(J),Yan… Cell Biol Toxicol 2026-05-08

...SYK signaling pathways were predominantly enriched among the differentially expressed proteins. Mechanistically, we show...

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