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Structural properties of two glycans in the fruits of jujube and their regulati…

Ruan(J),Zhang(P),Cheng(J),Yu(L),Wu(Y),Zheng(… Carbohydr Polym 2026-04-15

...Syk signaling pathway.

Translational immunothrombosis in autoimmune Heparin-Induced thrombocytopenia: …

Ahmadinia(M),Askarzade(A),Afsharara(H),Gholi… Clin Exp Med 2026-02-14

...Syk-BTK signaling and complement activation as central drivers of platelet activation and clearance. Preclinical and cli...

Large cyclic AMP-dependent increases in tyrosine-phosphorylated proteins are no…

Ueshiba(A),Nakao(R),Morikawa-Tomita(R),Kyogo… J Reprod Dev 2026-04-15

...SYK) inhibitor OXSI2 suppressed large cBiMPS-dependent increases in sperm tyrosine-phosphorylated proteins, in contrast ...

Bannakunin: a dual-target Kunitz inhibitor bridging anticoagulation (FXa/XIIa) …

He(M),He(Y),Feng(X),Li(Z),Lin(T),Yang(J),Luo… Cell Mol Biol Lett 2026-02-22

...Syk/PLCγ2 signalling pathway and the release of Ca2+, TXB2 and ATP. Furthermore, Bannakunin could effectively inhibit AD...

Sustained monocyte activation by persistent challenges with either oxLDL or fre…

Wu(Y),Geng(S),Atkinson(G),Caldwell(B),Wang(J… Immunohorizons 2026-02-12

...SYK-mTORC1-STAT3/5 signaling axis. Notably, the inflammatory state persisted even after stimulus withdrawal, suggesting ...

A biocompatible visible-light-crosslinkable dimethylglycine grafted gelatin hyd…

Zhao(M),Xia(S),Yun(L),Chen(X),Jian(X),Xu(F),… Int J Biol Macromol 2026-03-00

...Syk/NF-κB pathway. Consequently, M1 macrophage polarization is inhibited, creating a favorable osteoimmune microenvironm...

Assessing Aβ-independent effects of Module 42 on immune function in vitro.

Ajith(I),Bakshi(S),Mead(E),Gileadi(O),Katis(… Alzheimers Dement 2026-02-00

...Syk kinase activity. No M42 proteins had an effect on viability. Our results suggest an additional role for M42 in AD vi...

Safety, tolerability, pharmacokinetics and pharmacodynamics of the spleen tyros…

Carstensen-Aurèche(S),Litzenburger(T),De Sou… Br J Pharmacol 2026-06-00

...SYK) has broad biological functions in inflammation and immunity. The orally administered SYK inhibitor BI 894416 was in...

Inhibition of Sirpα expression enhances microglial phagocytic clearance of myel…

Jiang(W),Kong(D),Lou(J),Li(M),Jin(M),Zhu(L),… Int J Surg 2026-02-12

...Syk)/phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) pathway. Pharmacological inhibition of PI3K or Syk reve...

M2 macrophage-derived exosomes mitigate acute inflammation following ischemic s…

Song(J),Su(G),Chen(W),Xie(X),Zhang(Z) Front Neurol None

...Syk) and signal transducer and activator of transcription 3 (Stat3) in microglia, consequently reducing the production o...

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