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Detection of Rho GEF and GAP activity through a sensitive split luciferase assa…

Anderson(Erik L),Hamann(Michael J) Biochem J 2012-03-15

...Vav2, Trio and Asef) and GAPs [p190, Cdc42 GAP and PTPL1-associated RhoGAP]. The assay detected activities associated wi...

Proteomic analysis of microvesicles derived from human mesenchymal stem cells.

Kim(Han-Soo),Choi(Do-Young),Yun(So Jeong),Ch… J Proteome Res 2012-07-10

...VAV2); (3) cell adhesion (FN1, EZR, IQGAP1, CD47, integrins, and LGALS1/LGALS3); and (4) MSC-associated antigens (CD9, C...

Gene expression profile of mesenchymal stromal cells after co-culturing with in…

Cho(Kyung-Ah),Ju(Sun-Young),Ryu(Kyung-Ha),Wo… Mol Med Rep 2012-10-02

...Vav2 was upregulated. Our research provides information regarding the differential molecular mechanisms that regulate th...

Small GTPases Rap1 and RhoA regulate superoxide formation by Rac1 GTPases activ…

Li(Yi),Kim(Jae-Gyu),Kim(Hee-Jun),Moon(Mi-You… Free Radic Biol Med 2012-09-28

...Vav2 impaired GTP-Rac1 levels in response to 8CPT-2Me-cAMP/IOZ. Phosphorylation of RhoA activates Rac1 in response to IO...

VE-cadherin trans-interactions modulate Rac activation and enhancement of lung …

Birukova(Anna A),Tian(Yufeng),Dubrovskyi(Ole… J Cell Physiol 2012-10-29

...Vav2. Conversely, plating of pulmonary EC on surfaces coated with extracellular VE-cadherin domain further promoted ilop...

Identification of the Eph receptor pathway as a novel target for eicosapentaeno…

Doleman(Joanne F),Eady(John J),Elliott(Ruan … Nutr Metab (Lond) 2011-07-14

...Vav2 and EphA1 gene expression were identified as significantly altered by EPA treatment. Statistically significant chan...

Negative regulation of EGFR-Vav2 signaling axis by Cbl ubiquitin ligase control…

Duan(Lei),Raja(Srikumar M),Chen(Gengsheng),V… J Biol Chem 2011-01-31

...Vav2 and facilitates phospho-Vav2 ubiquitinylation. Cbl can also interact with Vav2 directly in a Cbl Tyr-700-dependent ...

The nuclear guanine nucleotide exchange factors Ect2 and Net1 regulate RhoB-med…

Srougi(Melissa C),Burridge(Keith) PLoS One 2011-09-01

...Vav2. Importantly, loss of Ect2 and Net1 via siRNA-mediated protein knock-down inhibited IR-induced increases in RhoB ac...

RhoB links PDGF signaling to cell migration by coordinating activation and loca…

Huang(Minzhou),Satchell(Lauren),Duhadaway(Ja… J Cell Biochem 2011-08-25

...Vav2 and Rac are also recruited to drive formation of circular dorsal and peripheral ruffles necessary for cell migratio...

Rap1-GTP-interacting adaptor molecule (RIAM) protein controls invasion and grow…

Hernández-Varas(Pablo),Coló(Georgina P),Bart… J Biol Chem 2011-07-28

...Vav2-RhoA-ROCK-myosin light chain pathway. Expression of constitutively active Vav2 and RhoA in cells depleted for RIAM ...

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