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Thrombosis-related gene signature predicts prostate cancer recurrence and immun…

Luo(Y),Chen(P),Situ(M),Zhuang(W),Huang(J),Wa… Inflamm Res 2026-02-19

...VAV2 in 22RV1 cells downregulated prothrombotic inflammatory factors (CXCL8, IL-6, and VEGF). Conditioned media from VAV...

VAV2-associated ncRNA network in the focal adhesion pathway is dysregulated in …

Mohammadi(P),Parvaz(N),MehdiKhani(F),Elahima… Discov Oncol 2026-05-27

...VAV2, a key guanine nucleotide exchange factor in the focal adhesion pathway, and to investigate its post-transcriptiona...

Convergent genetic and structural parameters of cardiovascular disease related …

Rao(RM),Kumar(N),P(SP),Rao(MJ),P(FH),N S(CS)… Biochem Biophys Res Commun 2026-09-17

...VAV2, and KCNQ1 demonstrated variant-specific destabilization affecting myocardial stress adaptation, sarcomeric mechani...

A Chemically Switchable Synthetic Condensate Platform for Reversible Protein Se…

Fukaya(Y),Yoshikawa(M),Aoki(K),Farrants(H),J… ACS Chem Biol 2026-01-16

...Vav2 and modulation of the cellular localization of endogenous ERK2-GFP generated by genome knock-in. Our results highli...

Uncovering novel germline variants associated with testicular germ cell tumors …

Cuevas-Estrada(B),Ríos-Rodríguez(JA),García-… NAR Cancer 2026-06-00

...VAV2, and CAPN8, with nominal associations. Three previously unreported variants: rs2273499 in ARFGAP1 (OR 3.72), rs1471...

Phosphorylated HAND1 contributes to trophoblast cell migration during placentat…

Ye(W),Zhu(C),Bao(Y),Li(L),An(Z),Song(Y),Xu(Q… Eur J Pharmacol 2026-07-15

...Vav2/Rac1/PAKs signaling, and the elevated capacity of HAND1 in inducing migration is dependent on its Serine/Threonine ...

Vav2 is a master regulator of repair against bacterial pore-forming toxins.

Kayejo(VG),Hensley(A),Katore(T),Keyel(PA) Life Sci Alliance 2026-09-00

...Vav2-inhibited cells. Blocking dysferlin or annexins failed to increase damage beyond Vav2 inhibition, suggesting Vav2 c...

VAV2 drives glycolytic reprogramming in esophageal squamous cell carcinoma via …

Liu(W),Hou(Y),Wang(B),Liu(F),Zheng(L),Wang(H… Cancer Metab 2026-07-09

...VAV2 functions as an oncoprotein promoting this metabolic switch in ESCC. VAV2 overexpression enhances glycolytic flux-e...

FARP1 mediates cMET-driven motility in androgen-independent prostate cancer cel…

Robayo(P),Kazanietz(MG),Baker(MJ),Cooke(M) Endocrinology 2026-05-26

...VAV2 as the main Rac-GEF effector of epidermal growth factor receptor in androgen-independent cellular models. An unbias...

Exploring the role of VAV2 rare variants in primary open-angle glaucoma: geneti…

Li(R),Chen(Y),Zhang(S),Ye(L),Tian(H),Li(Z),W… Sci China Life Sci 2026-01-00

...VAV2 variants linked to POAG (P_burden=1.40×l0-6). Functional analyses revealed that these variants disrupted normal VAV...

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